New insights on repeated acoustic injury: Augmentation of cochlear susceptibility and inflammatory reaction resultant of prior acoustic injury
In industrial and military settings, individuals who suffer from one episode of acoustic trauma
are likely to sustain another episode of acoustic stress, creating an opportunity for a potential …
are likely to sustain another episode of acoustic stress, creating an opportunity for a potential …
[HTML][HTML] Macrophages in noise-exposed cochlea: changes, regulation and the potential role
W He, J Yu, Y Sun, W Kong - Aging and disease, 2020 - ncbi.nlm.nih.gov
Acoustic trauma is an important physical factor leading to cochlear damage and hearing
impairments. Inflammation responds to this kind of cochlear damage stress. Macrophages …
impairments. Inflammation responds to this kind of cochlear damage stress. Macrophages …
[HTML][HTML] Noise-induced cochlear inflammation
Hearing loss is the most common sensory disability with considerable social and economic
implications. According to recent World Health Organization estimates, 360 million people …
implications. According to recent World Health Organization estimates, 360 million people …
Immune cell recruitment following acoustic trauma
SV Tornabene, K Sato, L Pham, P Billings, EM Keithley - Hearing research, 2006 - Elsevier
Acoustic trauma induces cochlear inflammation. We hypothesized that chemokines are
involved in the recruitment of leukocytes as part of a wound healing response. The cochleas …
involved in the recruitment of leukocytes as part of a wound healing response. The cochleas …
Characterisation of cochlear inflammation in mice following acute and chronic noise exposure
Oxidative stress has been established as the key mechanism of the cochlear damage
underlying noise-induced hearing loss, however, emerging evidence suggests that cochlear …
underlying noise-induced hearing loss, however, emerging evidence suggests that cochlear …
The time course of monocytes infiltration after acoustic overstimulation
Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to
protect hearing function from injury, including acoustic overstimulation. Cochlea …
protect hearing function from injury, including acoustic overstimulation. Cochlea …
Lower level noise exposure that produces only TTS modulates the immune homeostasis of cochlear macrophages
Noise exposure producing temporary threshold shifts (TTS) has been demonstrated to
cause permanent changes to cochlear physiology and hearing function. Several …
cause permanent changes to cochlear physiology and hearing function. Several …
Acoustic trauma augments the cochlear immune response to antigen
M Miyao, GS Firestein, EM Keithley - The Laryngoscope, 2008 - Wiley Online Library
Abstract Objectives/Hypothesis: To test whether noise‐exposure, which activates a cochlear
immune response with cytokine expression and infiltration of circulating leukocytes could …
immune response with cytokine expression and infiltration of circulating leukocytes could …
The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells
Cells of the immune system are present in the adult cochlea and respond to damage caused
by noise exposure. However, the types of immune cells involved and their locations within …
by noise exposure. However, the types of immune cells involved and their locations within …
Immune defense is the primary function associated with the differentially expressed genes in the cochlea following acoustic trauma
S Yang, Q Cai, RR Vethanayagam, J Wang, W Yang… - Hearing research, 2016 - Elsevier
Our previous RNA-sequencing analysis of the rat cochlear genes identified multiple
biological processes and molecular pathways in the cochlear response to acoustic …
biological processes and molecular pathways in the cochlear response to acoustic …