Functional involvement of central nervous system at high altitude

G Miscio, E Milano, J Aguilar, G Savia, G Foffani… - Experimental brain …, 2009 - Springer
Acute mountain sickness is a common discomfort experienced by unacclimatized persons
on ascent to high altitude. We tested the hypothesis that exposure to high altitude affects …

Evidence for cerebral edema, cerebral perfusion, and intracranial pressure elevations in acute mountain sickness

DM DiPasquale, SR Muza, AM Gunn, Z Li… - Brain and …, 2016 - Wiley Online Library
Introduction We hypothesized that cerebral alterations in edema, perfusion, and/or
intracranial pressure (ICP) are related to the development of acute mountain sickness …

Effect of hypoxia on the morphology of mouse striatal neurons

MG Wallace, KD Hartle, WM Snow, NL Ward, TL Ivanco - Neuroscience, 2007 - Elsevier
Symptoms of high altitude sickness including headache and neuropsychological dysfunction
are thought to result from prolonged exposure to hypoxia. In order to explain how the brain …

AltitudeOmics: cerebral autoregulation during ascent, acclimatization, and re-exposure to high altitude and its relation with acute mountain sickness

AW Subudhi, JL Fan, O Evero… - Journal of Applied …, 2014 - journals.physiology.org
Cerebral autoregulation (CA) acts to maintain brain blood flow despite fluctuations in
perfusion pressure. Acute hypoxia is thought to impair CA, but it is unclear if CA is affected …

Right temporal cerebral dysfunction heralds symptoms of acute mountain sickness

B Feddersen, H Ausserer, P Neupane… - Journal of …, 2007 - Springer
Acute mountain sickness (AMS) can occur during climbs to high altitudes and may seriously
disturb the behavioral and intellectual capacities of susceptible subjects. During a …

Frontiers of hypoxia research: acute mountain sickness

RC Roach, PH Hackett - Journal of Experimental Biology, 2001 - journals.biologists.com
Traditionally, scientists and clinicians have explored peripheral physiological responses to
acute hypoxia to explain the pathophysiological processes that lead to acute mountain …

Blood-brain barrier changes in high altitude

JV Lafuente, G Bermudez… - CNS & Neurological …, 2016 - ingentaconnect.com
Cerebral syndromes related to high-altitude exposure are becoming more frequent as the
number of trips to high altitudes has increased in the last decade. The commonest symptom …

Transient high altitude neurological dysfunction: an origin in the temporoparietal cortex

PG Firth, H Bolay - High Altitude Medicine & Biology, 2004 - liebertpub.com
This case report describes three separate episodes of isolated ataxia, hallucinations of
being accompanied by another person, and bilateral dressing apraxia occurring in a single …

EEG, ECG and oxygen concentration changes from sea level to a simulated altitude of 4000 m and back to sea level

C Guger, S Krausert, W Domej, G Edlinger… - Neuroscience …, 2008 - Elsevier
In order to describe how high altitude affects the body during a one night stay at 4000m
experiments were performed in a hypobaric chamber and compared to a study on Dachstein …

Sea-level assessment of dynamic cerebral autoregulation predicts susceptibility to acute mountain sickness at high altitude

NJ Cochand, M Wild, JV Brugniaux, PJ Davies… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Dynamic cerebral autoregulation is impaired in subjects who
develop acute mountain sickness (AMS), a neurological disorder characterized by …