Previous studies report the benefit of UVA1 phototherapy in treating acrosclerosis in patients
with systemic sclerosis. We carried out a retrospective study to examine the effectiveness of …

Background: Treatments currently used in acrosclerosis for patients with systemic sclerosis
(SS) are not very efficient and are associated with adverse effects. Several reports concern …

BACKGROUND: Increased collagen synthesis, vascular damage, and T-lymphocytic
infiltration contribute to the development of systemic sclerosis. Preliminary studies revealed …

Background: The presence of an inflammatory infiltrate consisting of helper T cells and a
dysregulated matrix metabolism leading to excessive deposition of collagen are two …

To the Editor, The introduction of phototherapy has substantially changed the therapeutic
response of localized scleroderma (LS). Systemic agents have been proposed for the …

Summary Background Ultraviolet (UV) A1 phototherapy is an effective anti‐inflammatory
treatment modality that influences fibroblast functions. Objectives To document the effects of …

Ultraviolet (UV) A1 phototherapy is effective for T‐cell‐mediated skin diseases such as
atopic dermatitis and mast cell‐mediated skin diseases such as mastocytoma. UVA1 …

Background: For treatment of localized scleroderma numerous treatments, including ones
with potentially hazardous side effects, are currently used with only limited success …

BACKGROUND: Ultraviolet (UV) A-1 phototherapy is now available for a variety of skin
diseases. Increasingly since 1995, there have been investigations of the efficacy of UVA-1 …

Abstract Background Recently, ultraviolet (UV) A1 phototherapy has been suggested as an
effective treatment for localized scleroderma (LS); however, the optimal dose of UVA1 still …