Epigenetics is a process that involves the regulation of gene expression without altering the
sequence of DNA. Numerous studies have documented that epigenetic mechanisms play a …

Epigenetics is a discipline that studies heritable changes in gene expression that do not
involve altering the DNA sequence. Over the past decade, researchers have shown that …

Simple Summary Non-coding RNAs (ncRNAs) are functional RNA molecules that occupy a
large fraction of the genome but are not translated into proteins. However, they serve key …

At the time of its construction in the 1950s, the central dogma of molecular biology was a
useful model that represented the current state of knowledge for the flow of genetic …

Only recently has it been uncovered that the mammalian transcriptome includes a large
number of noncoding RNAs (ncRNAs) that play a variety of important regulatory roles in …

RNA molecules that are unable to translate into proteins are classified as non‑coding RNA.
Non-coding RNA (ncRNA) genes include highly abundant and functionally important RNAs …

Epigenetic alterations, including aberrant DNA methylation and histone modification, play
key roles in the dysregulation of tumor-related genes, thereby affecting numerous cellular …

Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

Epigenetics is the study of heritable changes in gene expression that do not involve
changes in the underlying DNA sequence. The most studied epigenetic modifications …

Cancer represents a complex group of heterogeneous diseases. While many cancers share
fundamental biological processes (hallmarks of cancer) necessary for their development …