Periodontal bone defect is a common but longstanding healthcare issue since traditional
bone grafts have limited functionalities in regulating complex intraoral microenvironments …

Regeneration of periodontal tissue remains a challenge. Under periodontitis, osteoclasts are
overactivated and bone loss occurs. We incorporated sodium alendronate (Alen), a …

The development of biomimetic bone graft materials for periodontal tissue engineering is a
field of topical interest. In this study, we designed a dual-functionalized apatite …

Methods Herein, a facile and green design of engineered bone graft materials was
developed by integrating a biomimetic apatite nanocomposite with a smart-release coating …

Periodontal tissue regeneration is a major challenge in tissue engineering due to its
regenerated environment complexity. It aims to regenerate not only the supporting alveolar …

Tissue engineering technology provides a new method for periodontal regeneration. Finding
or preparing a suitable scaffold is the key to periodontal tissue engineering. Here, we use …

Preserving stable tooth-periodontal tissue integration is vital for maintaining alveolar bone
stability under physiological conditions. However, tooth extraction compromises this …

Despite bone's innate self-renewal capability, some periodontal pathologic and traumatic
defects' size inhibits full spontaneous regeneration. This current research characterized a …

Periodontitis is a common type of inflammatory bone loss induced by bacterial infection in
tooth-supporting tissue. Effective bone regeneration in the inflammatory microenvironment of …

Injectable antibacterial and osteoinductive hydrogels have received considerable attention
for promoting bone regeneration owing to their versatile functionalities. However, a current …