Nanoparticles as microcarriers for anticancer drugs

P Couvreur, L Roblot-Treupel, MF Poupon… - Advanced Drug Delivery …, 1990 - Elsevier
This paper surveys the current status of anticancer drug delivery by means of
polyalkylcyanoacrylate nanoparticles. In spite of the development of numerous …

Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly (butylcyanoacrylate) nanoparticles

C Melguizo, L Cabeza, J Prados, R Ortiz… - Drug design …, 2015 - Taylor & Francis
Doxorubicin (Dox) is widely used for the combined chemotherapy of solid tumors. However,
the use of these drug associations in lung cancer has low antitumor efficacy. To improve its …

Poly (alkyl cyanoacrylate) nanoparticles for delivery of anti-cancer drugs

RSR Murthy, LH Reddy - Nanotechnology for cancer therapy, 2006 - taylorfrancis.com
Poly (alkyl cyanoacrylates) with a higher alkyl chain length is relatively less toxic than those
with a lower alkyl chain length. Several interesting studies were reported on the usefulness …

Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate

X Li, R Li, X Qian, Y Ding, Y Tu, R Guo, Y Hu… - European Journal of …, 2008 - Elsevier
cis-Dichlorodiamminoplatinum (II)(cisplatin) has demonstrated extraordinary activities
against a variety of solid tumors. However, the clinical efficacy is contrasted by its toxicity …

Physicochemical characterization and in vitro behavior of daunorubicin-loaded poly (butylcyanoacrylate) nanoparticles

M Simeonova, G Ivanova, V Enchev, N Markova… - Acta Biomaterialia, 2009 - Elsevier
The design, preparation and characterization of poly (butylcyanoacrylate) nanoparticles as a
drug-delivery system for daunorubicin is reported. A range of light scattering [photon …

In vitro effect of imatinib mesylate loaded on polybutylcyanoacrylate nanoparticles on leukemia cell line K562

L Hasandoost, A Akbarzadeh, H Attar… - Artificial cells …, 2017 - Taylor & Francis
The study aimed to prepare imatinib mesylate-loaded polybutylcyanoacrylate (PBCA)
nanoparticles and evaluate their efficacy on leukemia cell line K562. The formulation was …

Cisplatin-loaded gelatin-poly (acrylic acid) nanoparticles: Synthesis, antitumor efficiency in vivo and penetration in tumors

D Ding, Z Zhu, Q Liu, J Wang, Y Hu, X Jiang… - European Journal of …, 2011 - Elsevier
Cisplatin (CDDP)-loaded gelatin-poly (acrylic acid)(GEL-PAA) nanoparticles were
successfully prepared by polymerizing acrylic acid in the presence of gelatin in aqueous …

Distribution of polyhexyl cyanoacrylate nanoparticles in nude mice bearing human osteosarcoma

EM Gipps, R Arshady, J Kreuter, P Groscurth… - Journal of …, 1986 - Elsevier
Abstract [14 C] Polyhexyl cyanoacrylate nanoparticles (PHCA), with diameters between 200
and 300 nm, were injected intravenously into nude mice bearing a human osteosarcoma …

Epirubicin loaded to pre-polymerized poly (butyl cyanoacrylate) nanoparticles: preparation and in vitro evaluation in human lung adenocarcinoma cells

G Yordanov, A Evangelatov, R Skrobanska - Colloids and Surfaces B …, 2013 - Elsevier
This article describes the preparation of epirubicin-loaded nanoparticles, prepared by
loading of the drug in pre-polymerized poly (butyl cyanoacrylate) nanoparticles, their …

Doxorubicin‐loaded poly (butylcyanoacrylate) nanoparticles produced by emulsifier‐free emulsion polymerization

SC Yang, HX Ge, Y Hu, XQ Jiang… - Journal of applied …, 2000 - Wiley Online Library
ABSTRACT: Doxorubicin‐loaded poly (butylcyanoacrylate)(PBCA) nanoparticles (NPs)
were prepared by an emulsifier‐free emulsion polymerization technique. The pH values of …