Preparation and evaluation of carboplatin biodegradable polymeric nanoparticles

BK Nanjwade, J Singh, KA Parikh, FV Manvi - International journal of …, 2010 - Elsevier
The present study was designed to evaluate targeting efficiency of carboplatin anticancer
drug. Drug was encapsulated in natural biodegradable polymer sodium alginate. The …

Highly stable core-surface-crosslinked nanoparticles as cisplatin carriers for cancer chemotherapy

P Xu, EA Van Kirk, S Li, WJ Murdoch, J Ren… - Colloids and Surfaces b …, 2006 - Elsevier
Cisplatin is a potent anticancer drug with low solubility in water. A new type of highly stable
polymer micelles, namely core-surface-crosslinked nanoparticles (SCNPs) made from …

Microneedle-mediated delivery of lipid-coated cisplatin nanoparticles for efficient and safe cancer therapy

X Lan, J She, D Lin, Y Xu, X Li, W Yang… - … applied materials & …, 2018 - ACS Publications
Cisplatin is the first-line chemotherapeutic agent, but its systemic toxicity and side effects
severely limit its clinical use. We report a microneedle technique to mediate the transdermal …

Stealth® PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting

MT Peracchia, E Fattal, D Desmaele, M Besnard… - Journal of Controlled …, 1999 - Elsevier
The aim of the present work was to investigate the biodistribution characteristics of PEG-
coated polycyanoacrylate nanoparticles prepared by the nanoprecipitation/solvent diffusion …

Anticancer drug-loaded chitosan nanoparticles for in vitro release, promoting antibacterial and anticancer activities

N Ahmad, MR Khan, S Palanisamy, S Mohandoss - Polymers, 2023 - mdpi.com
Targeted drug delivery to tumor cells may be possible using nanoparticles containing
human therapeutic drugs. The present study was carried out to develop cisplatin (CP) and 5 …

A modified double-emulsion method for the preparation of daunorubicin-loaded polymeric nanoparticle with enhanced in vitro anti-tumor activity

J Liu, Z Qiu, S Wang, L Zhou, S Zhang - Biomedical Materials, 2010 - iopscience.iop.org
The encapsulation of hydrophilic drug in polymeric nanoparticles with high loading remains
a challenge due to the rapid penetration of the drug to the external aqueous phase. In order …

Preparation and optimization of hyaluronic acid decorated irinotecan-loaded poly (lactic-co-glycolic acid) nanoparticles by microfluidics for cancer therapy applications

A Fabozzi, M Barretta, T Valente… - Colloids and Surfaces A …, 2023 - Elsevier
Polymer-based nanoparticles have been largely investigated in the cancer therapy field for
their features to generate colloidal delivery systems of hydrophobic drugs to improve drug …

Cisplatin-loaded nanoformulations for cancer therapy: A comprehensive review

M Pourmadadi, MM Eshaghi, E Rahmani… - Journal of Drug Delivery …, 2022 - Elsevier
Cisplatin, a genotoxic agent, is one of the most potent chemotherapy drugs, and has been
widely used alone or in combination with other antineoplastic drugs or radiation therapy to …

Preparation, characterization, and cytotoxic effects of liposomal nanoparticles containing cisplatin: an in vitro study

D Poy, A Akbarzadeh… - Chemical Biology & …, 2016 - Wiley Online Library
Cisplatin is a chemotherapeutic agent used for treating various malignancies. The study
aimed to prepare pegylated liposomal cisplatin and evaluate its efficacy against human …

Poly(lactic-co-glycolic acid) nanoparticles for sustained release of allyl isothiocyanate: characterization, in vitro release and biological activity

D Encinas-Basurto, J Ibarra, J Juarez… - Journal of …, 2017 - Taylor & Francis
The objective of this study is to establish the ability of entrap allyl isothiocyanate (AITC) into
polymeric nanoparticles to extend its shelf life and enhance its antiproliferative properties …