Background Lipid-polymer hybrid nanoparticles (LPHNP) are suitable for co-delivery of
hydrophilic and lipophilic drugs. The structural advantages of polymers and biomimetic …

The current study describes the impact of particle size and/or molecular targeting (epidermal
growth factor, EGF) on the in vivo transport of block copolymer micelles (BCMs) in athymic …

Nanoparticles represent promising carriers for controlled drug delivery. This work focuses on
the size and molecular mass characterization of polyalkylcyanoacrylate nanoparticles …

Nano polymeric micelles (nano PMs) help to increase accessibility to tumor sites, decrease
side effects and allow controlled drug dissemination over a long period of time. The aim of …

In recent decades, many novel methods by using nanoparticles (NPs) have been
investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential …

Hydrophilic drug delivery still remains a challenge; this either being attributed to the fragility
and poor cellular penetration of macromolecules, or to the unsuitable pharmacokinetics and …

Importance of the field: The lack of selective delivery of therapeutic molecules to cancer cells
remains a problem in cancer therapy. As a result of this non-selectivity, cytotoxic agents are …

To overcome the recurrence problem in bladder tumours; nanoparticles with positive surface
charge may improve interaction with biological membranes for intravesical administration …

Purpose Combination anticancer therapy is promising to generate synergistic anticancer
effects to maximize the treatment effect and overcome multidrug resistance. The aim of the …

The formulation of water insoluble organic compounds into nanoparticles has become a
widely established method for enhancing the delivery and efficacy of cancer therapeutics …