Application of cell-cell communication assays to problems of developmental toxicology

R Loch-Caruso - In Vitro Methods in Developmental Toxicology, 2019 - taylorfrancis.com
Gap junctions were initially defined by their morphology in transmission electron
micrographs, where they appear as very close appositions of membranes of adjacent cells …

Gap junctions and development

F Allen - Science Progress (1933-), 1987 - JSTOR
The transfer of ions and small molecules between animal cells is generally thought to be
mediated by protein structures in the plasma membranes called gap junctions. These may …

In vitro inhibition of gap junctional intercellular communication by chemical carcinogens

MR Na, SK Koo, DY Kim, S Dai Park, KW Kang, CO Joe - Toxicology, 1995 - Elsevier
This study was conducted to assess the effects of chemical carcinogens on the gap junction-
mediated intercellular communication in cultured mammalian cells. The method of scrape …

Interruption of cell-cell communication in Chinese hamster V79 cells by various alkyl glycol ethers: implications for teratogenicity.

R Loch-Caruso, JE Trosko… - Environmental Health …, 1984 - ehp.niehs.nih.gov
Intercellular communication most likely plays a significant coordinating role in
morphogenesis. Blockage of a specific type of intercellular communication, that mediated by …

[引用][C] The role of gap junctions in development

S Caveney - Annual review of physiology, 1985 - annualreviews.org
The gap junction, a membrane specialization found in most growing and mature metazoan
tissues, is the site of dynamic cell-to-cell channels permeable to inorganic ions and small …

Gap junction ultrastructure in three states of conductance

RC Berdan, S Caveney - Cell and tissue research, 1985 - Springer
Junctional conductance between the epidermal cells of the beetle Tenebrio molitor is raised
after exposure to the hormone 20-hydroxyecdysone and lowered reversibly by exposure to …

Effects of a teratogen on [3H] uridine nucleotide transfer between human embryonal cells and on gap junctions

F Welsch, DB Stedman, JL Carson - Experimental cell research, 1985 - Elsevier
Intercellular communication (IC) mediated by gap junctions (gj) occurs during embryonal
development and appears to be important for normal differentiation through the exchange of …

Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implications

JE Trosko, BV Madhukar, CC Chang - Life sciences, 1993 - Elsevier
During the evolution of single-celled organisms to multicellular metazoans, a family of highly
conserved genes coding for proteins (connexins), which as hexameric units (connexons) …

Gap junctional communication and development

SC Guthrie, NB Gilula - Trends in neurosciences, 1989 - cell.com
Embryonic development requires extensive interaction between cells; cell-to-cell
communication through gap junctions may be one mechanism involved. Much correlative …

Morphological transformation and effect on gap junction intercellular communication in Syrian hamster embryo cells as screening tests for carcinogens devoid of …

E Rivedal, SO Mikalsen, T Sanner - Toxicology in Vitro, 2000 - Elsevier
A large fraction of chemicals observed to cause cancer in experimental animals is devoid of
mutagenic activity. It is therefore of importance to develop methods that can be used to …