Application of cell-cell communication assays to problems of developmental toxicology
R Loch-Caruso - In Vitro Methods in Developmental Toxicology, 2019 - taylorfrancis.com
Gap junctions were initially defined by their morphology in transmission electron
micrographs, where they appear as very close appositions of membranes of adjacent cells …
micrographs, where they appear as very close appositions of membranes of adjacent cells …
Gap junctions and development
F Allen - Science Progress (1933-), 1987 - JSTOR
The transfer of ions and small molecules between animal cells is generally thought to be
mediated by protein structures in the plasma membranes called gap junctions. These may …
mediated by protein structures in the plasma membranes called gap junctions. These may …
In vitro inhibition of gap junctional intercellular communication by chemical carcinogens
This study was conducted to assess the effects of chemical carcinogens on the gap junction-
mediated intercellular communication in cultured mammalian cells. The method of scrape …
mediated intercellular communication in cultured mammalian cells. The method of scrape …
Interruption of cell-cell communication in Chinese hamster V79 cells by various alkyl glycol ethers: implications for teratogenicity.
R Loch-Caruso, JE Trosko… - Environmental Health …, 1984 - ehp.niehs.nih.gov
Intercellular communication most likely plays a significant coordinating role in
morphogenesis. Blockage of a specific type of intercellular communication, that mediated by …
morphogenesis. Blockage of a specific type of intercellular communication, that mediated by …
[引用][C] The role of gap junctions in development
S Caveney - Annual review of physiology, 1985 - annualreviews.org
The gap junction, a membrane specialization found in most growing and mature metazoan
tissues, is the site of dynamic cell-to-cell channels permeable to inorganic ions and small …
tissues, is the site of dynamic cell-to-cell channels permeable to inorganic ions and small …
Gap junction ultrastructure in three states of conductance
RC Berdan, S Caveney - Cell and tissue research, 1985 - Springer
Junctional conductance between the epidermal cells of the beetle Tenebrio molitor is raised
after exposure to the hormone 20-hydroxyecdysone and lowered reversibly by exposure to …
after exposure to the hormone 20-hydroxyecdysone and lowered reversibly by exposure to …
Effects of a teratogen on [3H] uridine nucleotide transfer between human embryonal cells and on gap junctions
F Welsch, DB Stedman, JL Carson - Experimental cell research, 1985 - Elsevier
Intercellular communication (IC) mediated by gap junctions (gj) occurs during embryonal
development and appears to be important for normal differentiation through the exchange of …
development and appears to be important for normal differentiation through the exchange of …
Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implications
JE Trosko, BV Madhukar, CC Chang - Life sciences, 1993 - Elsevier
During the evolution of single-celled organisms to multicellular metazoans, a family of highly
conserved genes coding for proteins (connexins), which as hexameric units (connexons) …
conserved genes coding for proteins (connexins), which as hexameric units (connexons) …
Gap junctional communication and development
SC Guthrie, NB Gilula - Trends in neurosciences, 1989 - cell.com
Embryonic development requires extensive interaction between cells; cell-to-cell
communication through gap junctions may be one mechanism involved. Much correlative …
communication through gap junctions may be one mechanism involved. Much correlative …
Morphological transformation and effect on gap junction intercellular communication in Syrian hamster embryo cells as screening tests for carcinogens devoid of …
E Rivedal, SO Mikalsen, T Sanner - Toxicology in Vitro, 2000 - Elsevier
A large fraction of chemicals observed to cause cancer in experimental animals is devoid of
mutagenic activity. It is therefore of importance to develop methods that can be used to …
mutagenic activity. It is therefore of importance to develop methods that can be used to …