T regulatory cells suppress a variety of immune responses to self-antigens and play a role in
peripheral tolerance maintenance by limiting autoimmune disorders, and other pathological …

Regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3) play a
requisite role in the maintenance of immunological homeostasis and prevention of …

The discovery of FOXP3+ regulatory T (Treg) cells as a distinct cell lineage with a central
role in regulating immune responses provided a deeper understanding of self-tolerance …

T regulatory (Treg) cells are central to the maintenance of immune homeostasis. The
transcription factor forkhead box P3 (Foxp3) is essential for specifying the Treg cell lineage …

Regulatory T (Treg) cells represent an essential component of peripheral tolerance. Given
their potently immunosuppressive functions that is orchestrated by the lineage-defining …

Naturally occurring CD4+ regulatory T cells (Tregs), which specifically express the
transcription factor FoxP3 in the nucleus and CD25 and CTLA-4 on the cell surface, are a …

Foxp3-expressing regulatory T cells (Tregs) were originally identified as critical in
maintaining self-tolerance and immune homeostasis. The immunosuppressive functions of …

Abstract Forkhead box P3 (FOXP3)-expressing regulatory T (TReg) cells have a pivotal role
in the regulation of immune responses and in the maintenance of immunological self …

The immune system has evolved to mount an effective defense against pathogens and to
minimize deleterious immune-mediated inflammation caused by commensal …

Regulatory T (Treg) cells that express the transcription factor forkhead box protein P3
(FOXP3) play an essential role in enforcing immune tolerance to self tissues, regulating host …