Azithromycin during acute chronic obstructive pulmonary disease exacerbations requiring hospitalization (BACE). A multicenter, randomized, double-blind, placebo …

K Vermeersch, M Gabrovska, J Aumann… - American journal of …, 2019 - atsjournals.org
Rationale: Azithromycin prevents acute exacerbations of chronic obstructive pulmonary
disease (AECOPDs); however, its value in the treatment of an AECOPD requiring …

Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy

MLK Han, N Tayob, S Murray… - American journal of …, 2014 - atsjournals.org
Rationale: Daily azithromycin decreases acute exacerbations of chronic obstructive
pulmonary disease (AECOPD), but long-term side effects are unknown. Objectives: To …

Long-term azithromycin therapy in patients with severe COPD and repeated exacerbations

X Pomares, C Montón, M Espasa… - … journal of chronic …, 2011 - Taylor & Francis
Background The aim of this study was to determine whether long-term intermittent
azithromycin therapy reduces the frequency of exacerbation in severe chronic obstructive …

[HTML][HTML] Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease

N Naderi, D Assayag, Z Kaddaha, A Joubert… - Respiratory …, 2018 - Elsevier
Rationale According to clinical trials, azithromycin taken daily for 1 year, decreased
exacerbations of chronic obstructive pulmonary disease (COPD). Objectives Effectiveness …

Azithromycin for the prevention of COPD exacerbations: the good, bad, and ugly

SP Taylor, E Sellers, BT Taylor - The American Journal of Medicine, 2015 - Elsevier
Long-term azithromycin therapy has been shown to reduce exacerbations of chronic
obstructive pulmonary disease (COPD), and is recommended by recent society guidelines …

Azithromycin for prevention of exacerbations of COPD

RK Albert, J Connett, WC Bailey… - … England Journal of …, 2011 - Mass Medical Soc
Background Acute exacerbations adversely affect patients with chronic obstructive
pulmonary disease (COPD). Macrolide antibiotics benefit patients with a variety of …

[HTML][HTML] Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo–a post-hoc analysis of the BACE …

K Vermeersch, A Belmans, K Bogaerts, I Gyselinck… - Respiratory …, 2019 - Springer
Background In the BACE trial, a 3-month (3 m) intervention with azithromycin, initiated at the
onset of an infectious COPD exacerbation requiring hospitalization, decreased the rate of a …

[HTML][HTML] Systemic and functional effects of continuous azithromycin treatment in patients with severe chronic obstructive pulmonary disease and frequent …

E Cuevas, D Huertas, C Montón, A Marin… - Frontiers in …, 2023 - frontiersin.org
Background Continuous treatment with azithromycin may lead to fewer acute exacerbations
of chronic obstructive pulmonary disease (AECOPD), but little is known of its impact on …

Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): a randomised, double-blind …

S Uzun, RS Djamin, JAJW Kluytmans… - The Lancet …, 2014 - thelancet.com
Background Macrolide resistance is an increasing problem; there is therefore debate about
when to implement maintenance treatment with macrolides in patients with chronic …

Long-term azithromycin use in patients with chronic obstructive pulmonary disease and tracheostomy

F Blasi, D Bonardi, S Aliberti, P Tarsia… - Pulmonary …, 2010 - Elsevier
Patients with Chronic Obstructive Pulmonary Disease (COPD) and tracheostomy are at high
risk for exacerbations and hospitalizations. Macrolide treatment has shown to reduce …