Intraspecies transcriptional profiling reveals key regulators of Candida albicans pathogenic traits
The human commensal and opportunistic fungal pathogen Candida albicans displays
extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA …
extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA …
Genome-wide functional analysis in Candida albicans
Candida albicans is an important etiological agent of superficial and life-threatening
infections in individuals with compromised immune systems. To date, we know of several …
infections in individuals with compromised immune systems. To date, we know of several …
Infection-related gene expression in Candida albicans
Research into the major fungal pathogen, Candida albicans has firmly entered the post-
genomics era. The current challenge is to apply these technologies to the analysis of C …
genomics era. The current challenge is to apply these technologies to the analysis of C …
Budding off: bringing functional genomics to Candida albicans
MZ Anderson, RJ Bennett - Briefings in functional genomics, 2016 - academic.oup.com
Candida species are the most prevalent human fungal pathogens, with Candida albicans
being the most clinically relevant species. Candida albicans resides as a commensal of the …
being the most clinically relevant species. Candida albicans resides as a commensal of the …
Identifying infection-associated genes of Candida albicans in the postgenomic era
D Wilson, S Thewes, K Zakikhany, C Fradin… - FEMS yeast …, 2009 - academic.oup.com
The human pathogenic yeast Candida albicans can cause an unusually broad range of
infections reflecting a remarkable potential to adapt to various microniches within the human …
infections reflecting a remarkable potential to adapt to various microniches within the human …
Evolution and strain diversity advance exploration of Candida albicans biology
MZ Anderson, SM Dietz - Msphere, 2024 - journals.asm.org
Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …
and its phenotypic consequences on members of a species. Yeasts that cause significant …
Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory Circuit
JC Pérez, CA Kumamoto, AD Johnson - PLoS biology, 2013 - journals.plos.org
Systemic, life-threatening infections in humans are often caused by bacterial or fungal
species that normally inhabit a different locale in our body, particularly mucosal surfaces. A …
species that normally inhabit a different locale in our body, particularly mucosal surfaces. A …
Candida albicans natural diversity: a resource to dissect fungal commensalism and pathogenesis
E Lindemann-Perez, JC Perez - Current Opinion in Microbiology, 2024 - Elsevier
Candida albicans is a ubiquitous fungus of humans. It is not only a component of the oral
and intestinal microbiota of most healthy adults but also a major cause of mucosal disorders …
and intestinal microbiota of most healthy adults but also a major cause of mucosal disorders …
Recent Developments in Molecular Genetics of Candida Albicans
MD De Backer, PT Magee, J Pla - Annual Reviews in …, 2000 - annualreviews.org
▪ Abstract The frequency of opportunistic infections caused by the fungus Candida albicans
is very high and is expected to continue to increase as the number of immunocompromised …
is very high and is expected to continue to increase as the number of immunocompromised …
A Versatile Overexpression Strategy in the Pathogenic Yeast Candida albicans: Identification of Regulators of Morphogenesis and Fitness
Candida albicans is the most frequently encountered human fungal pathogen, causing both
superficial infections and life-threatening systemic diseases. Functional genomic studies …
superficial infections and life-threatening systemic diseases. Functional genomic studies …