Intraspecies transcriptional profiling reveals key regulators of Candida albicans pathogenic traits

JM Wang, AL Woodruff, MJ Dunn, RJ Fillinger… - MBio, 2021 - Am Soc Microbiol
The human commensal and opportunistic fungal pathogen Candida albicans displays
extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA …

Genome-wide functional analysis in Candida albicans

TE Motaung, R Ells, CH Pohl, J Albertyn, TJ Tsilo - Virulence, 2017 - Taylor & Francis
Candida albicans is an important etiological agent of superficial and life-threatening
infections in individuals with compromised immune systems. To date, we know of several …

Infection-related gene expression in Candida albicans

AJP Brown, FC Odds, NAR Gow - Current opinion in microbiology, 2007 - Elsevier
Research into the major fungal pathogen, Candida albicans has firmly entered the post-
genomics era. The current challenge is to apply these technologies to the analysis of C …

Budding off: bringing functional genomics to Candida albicans

MZ Anderson, RJ Bennett - Briefings in functional genomics, 2016 - academic.oup.com
Candida species are the most prevalent human fungal pathogens, with Candida albicans
being the most clinically relevant species. Candida albicans resides as a commensal of the …

Identifying infection-associated genes of Candida albicans in the postgenomic era

D Wilson, S Thewes, K Zakikhany, C Fradin… - FEMS yeast …, 2009 - academic.oup.com
The human pathogenic yeast Candida albicans can cause an unusually broad range of
infections reflecting a remarkable potential to adapt to various microniches within the human …

Evolution and strain diversity advance exploration of Candida albicans biology

MZ Anderson, SM Dietz - Msphere, 2024 - journals.asm.org
Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …

Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory Circuit

JC Pérez, CA Kumamoto, AD Johnson - PLoS biology, 2013 - journals.plos.org
Systemic, life-threatening infections in humans are often caused by bacterial or fungal
species that normally inhabit a different locale in our body, particularly mucosal surfaces. A …

Candida albicans natural diversity: a resource to dissect fungal commensalism and pathogenesis

E Lindemann-Perez, JC Perez - Current Opinion in Microbiology, 2024 - Elsevier
Candida albicans is a ubiquitous fungus of humans. It is not only a component of the oral
and intestinal microbiota of most healthy adults but also a major cause of mucosal disorders …

Recent Developments in Molecular Genetics of Candida Albicans

MD De Backer, PT Magee, J Pla - Annual Reviews in …, 2000 - annualreviews.org
▪ Abstract The frequency of opportunistic infections caused by the fungus Candida albicans
is very high and is expected to continue to increase as the number of immunocompromised …

A Versatile Overexpression Strategy in the Pathogenic Yeast Candida albicans: Identification of Regulators of Morphogenesis and Fitness

M Chauvel, A Nesseir, V Cabral, S Znaidi, S Goyard… - 2012 - journals.plos.org
Candida albicans is the most frequently encountered human fungal pathogen, causing both
superficial infections and life-threatening systemic diseases. Functional genomic studies …