[HTML][HTML] Torque-Teno virus viral load as a potential endogenous marker of immune function in solid organ transplantation

O Rezahosseini, CH Drabe, SS Sørensen… - Transplantation …, 2019 - Elsevier
Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …

Torque teno virus is associated with the state of immune suppression early after liver transplantation

P Ruiz, M Martínez‐Picola, M Santana… - Liver …, 2019 - Wiley Online Library
The development of noninvasive biomarkers that reflect the state of immunosuppression (IS)
remains an unmet need in liver transplantation (LT). Torque Teno virus (TTV) is a highly …

[HTML][HTML] Torque teno virus loads after kidney transplantation predict allograft rejection but not viral infection

AL van Rijn, HF Wunderink, IA Sidorov… - Journal of Clinical …, 2021 - Elsevier
The main challenge of immunosuppressive therapy after solid organ transplantation is to
create a new immunological balance that prevents organ rejection and does not promote …

Torque teno virus load as marker of rejection and infection in solid organ transplantation–A systematic review and meta‐analysis

AL Van Rijn, R Roos, FW Dekker… - Reviews in Medical …, 2023 - Wiley Online Library
Balancing immunosuppression to prevent rejection in solid organ transplant (SOT)
recipients remains challenging. Torque teno virus (TTV), a commensal non‐pathogenic …

[HTML][HTML] Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients—a prospective observational trial

K Doberer, M Schiemann, R Strassl… - American Journal of …, 2020 - Elsevier
The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Quantification of torque teno virus viremia as a prospective biomarker for infectious disease in kidney allograft recipients

R Strassl, M Schiemann, K Doberer… - The Journal of …, 2018 - academic.oup.com
Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

Viruses, friends, and foes: The case of Torque Teno Virus and the net state of immunosuppression

N Redondo, D Navarro, JM Aguado… - Transplant Infectious …, 2022 - Wiley Online Library
New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

[HTML][HTML] Torque teno virus load is associated with subclinical alloreactivity in kidney transplant recipients: a prospective observational trial

K Doberer, F Haupenthal, M Nackenhorst… - …, 2021 - journals.lww.com
Background. Nonpathogenic torque teno viruses (TTVs) are highly prevalent in transplant
recipients and associated with immunosuppression. Studies in kidney transplant patients …

Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Dynamics of Torque Teno virus viremia could predict risk of complications after allogeneic hematopoietic stem cell transplantation

R Gilles, M Herling, U Holtick, E Heger… - Medical microbiology …, 2017 - Springer
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an established treatment
option for several hematological diseases. However, the first year post-transplantation is …