The present paper evaluates the effect of physical activity on the increase of the conditioned
rewarding effects of cocaine induced by intermittent social stress and on the …

Social defeat is considered the most representative animal model for studying the
consequences of social stress. Intermittent social defeat (ISD) has proved to enhance the …

Besides significant benefits to physical health, exercise promotes mental health, reduces
symptoms of mental illness, and enhances psychological development. Exercise can offset …

Previous literature suggests that free access to a running wheel can attenuate the
behavioral responsiveness to addictive drugs in rodents. In a few studies, wheel-running …

A novel approach to reduce the incidence of substance use disorders is to promote
resilience to stress using environmental resources such as physical exercise. In the present …

Previous studies have shown that exposure to social defeat (SD), a model of social stress,
produces a long-term increase in the consumption of ethanol, most likely through an …

Exercise promotes stress resistance and is associated with reduced anxiety and reduced
depression in both humans and in animal models. Despite the fact that dysfunction within …

Acute or chronic exposure to stress can increase the risk to develop major depressive
disorder, a severe, recurrent and common psychiatric condition. Depression places an …

Recent evidence has revealed the impact of exercise in alleviating anxiety and mood
disorders; however, the exercise protocol that exerts such benefit is far from known. The …

Rodents housed with a running wheel can exhibit attenuated cocaine seeking and cocaine-
induced psychomotor activation. However, the longevity of such a protection and the …