Recently, the availability of protocols supporting genetic complementation of Eimeria has
raised the prospect of generating transgenic parasite lines which can function as vaccine …

Background Live anticoccidial vaccines have been a tremendous success for disease
prevention. The establishment of the reverse genetic manipulation platform has enabled the …

Vaccine delivery is critical in antigen discovery and vaccine efficacy and safety. The diversity
of infectious diseases in humans and livestock has required the development of varied …

Background Poultry coccidiosis is a parasitic enteric disease with a highly negative impact
on chicken production. In-feed chemoprophylaxis remains the primary method of control, but …

Vaccination of poultry against coccidiosis caused by the Eimeria species is almost entirely
based upon varied formulations of live parasites. The recent development of a series of …

Eimeria is a genus of apicomplexan parasites that contains a large number of species, most
of which are absolutely host‐specific. Seven species have been recognized to infect …

Eimeria parasites are obligate intracellular apicomplexan protists that can cause coccidiosis,
resulting in substantial economic losses in the poultry industry annually. As the component …

Immunity to Eimeria is species-specific, and chickens with immunity to one species of
Eimeria remain susceptible to other Eimeria species. This presents a major challenge in the …

Avian coccidiosis is an intestinal disease caused by protozoa of the genus Eimeria. To
investigate the potential of recombinant protein vaccines to control coccidiosis, we cloned 2 …

Live attenuated coccidiosis vaccines could be used as powerful carriers, expressing
exogenous viral and bacterial antigens, to induce protective immunity against pathogenic …