Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …

Background Schizophrenia is a complex polygenic disorder with subtle, distributed
abnormalities in brain morphology. There are indications of shared genetic architecture …

Genome-wide association studies (GWAS) have identified many genomic loci associated
with risk for schizophrenia, but unambiguous identification of the relationship between …

Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …

Genome-wide association studies of schizophrenia (GWAS) have revealed the role of rare
and common genetic variants, but the functional effects of the risk variants remain to be …

It is widely thought that alleles that influence susceptibility to common diseases, including
schizophrenia, will frequently do so through effects on gene expression. As only a small …

Chromosome 10q24. 32‐q24. 33 is one of the most robustly supported risk loci to emerge
from genome‐wide association studies (GWAS) of schizophrenia. However, extensive …

Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …

Schizophrenia is a highly complex inheritable disease characterized by numerous genetic
susceptibility elements, each contributing a modest increase in risk for the disease. Although …

Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …