Transcriptional profiling of Staphylococcus aureus treated with cell wall-active antibiotics
identified the 2-component system, VraSR, as one of the key players in response to …

DNA microarray covering the whole genome of Staphylococcus aureus strain N315 was
prepared to investigate transcription profiles. The microarray analyses revealed that …

Exposure of Staphylococcus aureus to cell wall inhibitors induces massive overexpression
of a number of genes, provided that the VraSR two-component sensory regulatory system is …

The objective of this study was to comprehensively identify the target genes regulated by the
two-component regulatory system VraSR in Staphylococcus aureus and to clarify the role of …

ABSTRACT The VraS/VraR two-component system (VraSR) regulates transcriptional
induction of penicillin-binding protein 2 (encoded by pbp2) by vancomycin in …

Staphylococcus aureus infections caused by strains that are resistant to all forms of
penicillin, so-called methicillin-resistant S. aureus (MRSA) strains, have become common …

In Staphylococcus aureus the VraSR two-component system acts as a sentinel that can
rapidly sense cell wall peptidoglycan damage and coordinate a response to enhance the …

Staphylococcus aureus remains a clinical scourge. Recent studies have revealed that S.
aureus is capable of mounting a response to antibiotics that target cell wall peptidoglycan …

Background Staphylococcus aureus remains a medical challenge in the treatment of
bacterial infections. It has acquired resistance to commonly used antibiotics, and to those …

The exposure of Staphylococcus aureus to a broad range of cell wall-damaging agents
triggers the induction of a cell wall stress stimulon (CWSS) controlled by the VraSR two …