C-phycocyanin ameliorates cyclophosphamide-induced liver injury and metabolic disorder through the modulation of the gut microbiota in mice

X Li, M Zhao, Z Ding, X Wang, Z Zhang - Algal Research, 2023 - Elsevier
Cyclophosphamide (CTX) is an alkylating agent of nitrogen mustard with broad anti-tumor
activity, but excessive or prolonged use can result in toxic side effects such as bone marrow …

[HTML][HTML] C-phycocyanin alleviated cisplatin-induced oxidative stress and inflammation via gut microbiota—metabolites axis in mice

Y Zhang, L Li, S Qin, J Yuan, X Xie, F Wang, S Hu… - Frontiers in …, 2022 - frontiersin.org
C-phycocyanin is a natural protein extracted from Spirulina platensis. We aim to investigate
the preventive effect of C-phycocyanin on cisplatin chemotherapy-induced oxidative …

Protective effects of C-phycocyanin on alcohol-induced subacute liver injury in mice

D Xia, B Liu, W Xin, T Liu, J Sun, N Liu, S Qin… - Journal of applied …, 2016 - Springer
Excessive and long-term alcohol consumption leads to liver disease and low immunity.
Extensive evidence suggests that C-phycocyanin (C-PC), a chromophore phycocyanobilin …

C-phycocyanin from Spirulina maxima protects hepatocytes against oxidative damage induced by H2O2 in vitro

Y Ou, S Zheng, L Lin, Q Li - Biomedicine & Preventive Nutrition, 2011 - Elsevier
Oxidative damage is implicated in the pathogenesis of various liver injuries. C-phycocyanin
(C-PC), which is a potent free radical scavenger and antioxidant agent, has been reported to …

Protective effects of C-phycocyanin on alcohol-induced acute liver injury in mice

D Xia, B Liu, X Luan, J Sun, N Liu, S Qin… - Chinese Journal of …, 2016 - Springer
Excessive alcohol consumption leads to liver disease. Extensive evidence suggests that C-
phycocyanin (C-PC), a chromophore phycocyanobilin derived from Spirulina platensis …

Phycocyanin ameliorates mouse colitis via phycocyanobilin-dependent antioxidant and anti-inflammatory protection of the intestinal epithelial barrier

W Guo, M Zeng, S Zhu, S Li, Y Qian, H Wu - Food & function, 2022 - pubs.rsc.org
Phycocyanin is a typical microalgal active compound with antioxidant and anti-inflammatory
efficacy, and the pigment moiety phycocyanobilin has been recently proposed as its active …

The effect of C-phycocyanin on microglia activation is mediated by toll-like receptor 4

A Piovan, R Filippini, C Argentini, S Moro… - International Journal of …, 2022 - mdpi.com
The blue-green alga Spirulina platensis is rich in phycocyanins, that exhibit a wide range of
pharmacological actions. C-phycocyanin (C-PC), in particular, possesses hepatoprotective …

Potential use of C-phycocyanin in non-alcoholic fatty liver disease

P Ma, R Huang, J Jiang, Y Ding, T Li, Y Ou - Biochemical and Biophysical …, 2020 - Elsevier
Abstract C-phycocyanin (C-PC) is a kind of photosynthetically assisted pigment, which is
ubiquitous in cyanobacteria cells. We investigated the effect of C-PC on non-alcoholic fatty …

The alleviative effect of C-phycocyanin peptides against TNBS-induced inflammatory bowel disease in zebrafish via the MAPK/Nrf2 signaling pathways

F Xu, F Yang, Y Qiu, C Wang, Q Zou, L Wang… - Fish & Shellfish …, 2024 - Elsevier
Introduction Ulcerative colitis (UC) is an incurable and highly complex chronic inflammatory
bowel disease (IBD) affecting millions of people worldwide. C-phycocyanin (C-PC) has been …

Hepatoprotective and antioxidative effects of C-phycocyanin from Arthrospira maxima SAG 25780 in CCl4-induced hepatic damage rats

S Nagaraj, P Arulmurugan, MG Rajaram… - … & Preventive Nutrition, 2012 - Elsevier
The efficacy of C-phycocyanin obtained from Arthrospira maxima SAG 25780 was evaluated
on the levels of lipid peroxidation, and antioxidant parameters as well as histopathological …