Stress confers risk for the development and progression of Alzheimer's disease (AD).
Relative to men, women are disproportionately more likely to be diagnosed with this …

Chronic stress may be a risk factor for developing Alzheimer's disease (AD), but most
studies of the effects of stress in models of AD utilize acute adverse stressors of …

Clinical studies indicate that Alzheimer's disease (AD) disproportionately affects women in
both disease prevalence and severity, but the mechanisms underlying this sex divergence …

The risk of Alzheimer's disease (AD) is higher in women than in men, a sex difference that
likely results from the effects of sex steroid hormones. To investigate this relationship, we first …

Many stress-related neuropsychiatric disorders display pronounced sex differences in their
frequency and clinical symptoms. Glucocorticoids are primary stress hormones that have …

Activation of the hypothalamic-pituitary-adrenal (HPA) axis occurs in response to the
organism's innate need for homeostasis. The glucocorticoids (GCs) that are released into …

Memory impairment in Alzheimer's disease patients is thought to be associated with the
accumulation of amyloid-beta peptides and tau proteins. However, inconsistent reports of …

Approximately two-thirds of those suffering with Alzheimer's disease (AD) are women,
however, the biological mechanisms underlying this sex divergence of AD prevalence …

Decreases in testosterone and 17β‐oestradiol (E 2) are associated with an increased risk for
A lzheimer's disease (AD), which has been attributed to an increase in β‐amyloid and tau …

We sought to determine if sex impacts the cognitive and neuropathological phenotype of the
3xTg-AD mice. We find that male and female 3xTg-AD mice show comparable impairments …