In this study, we investigated mice of the TgCRND8 line, an APP transgenic mouse model of
Alzheimer's disease (AD), with respect to behavioral, endocrinological, and …

Stress may promote emotional and cognitive disturbances, which differ by sex. Adverse
outcomes, including memory disturbances, are typically observed following chronic stress …

Chronic psychosocial stress is increasingly being recognised as a risk factor for sporadic
Alzheimer's disease (AD). The hypothalamic–pituitary–adrenal axis (HPA axis) is the major …

Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Background: The prevalence of Alzheimer's disease (AD) is greater in women compared to
men, but the reasons for this remain unknown. This sex difference has been widely …

In vulnerable individuals, chronic and persistent stress is an established risk factor for
disorders that are comorbid with Alzheimer's disease (AD), such as hypertension, obesity …

Converging evidence suggests that females and males show different responses to stress;
however, little is known about the mechanism underlying the sexually dimorphic effects of …

Cognitive processes associated with prefrontal cortex and hippocampus decline with age
and are vulnerable to disruption by stress. The stress/stress hormone/allostatic load …

Chronic stress is implicated as a risk factor for Alzheimer's disease (AD) and other
neurodegenerative disorders. Although the specific mechanisms linking stress exposure …

Normal, age-related depletion of the androgen testosterone is a risk factor for Alzheimer's
disease (AD) in men. Previously, we reported that experimental androgen depletion …