[HTML][HTML] A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases
Background Exclusive breastfeeding of infants under 6 months of age is recommended by
the World Health Organization. In 2021, over 300 million combined incident cases of …
the World Health Organization. In 2021, over 300 million combined incident cases of …
[HTML][HTML] Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Background: Data surrounding the exposure of the breastfed infant to drugs and any
associated risks are sparse. Drugs usually are transferred to milk in small quantities, and …
associated risks are sparse. Drugs usually are transferred to milk in small quantities, and …
Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies
Objectives The objectives of this study were to summarize antiretroviral drug concentrations
in breast milk (BM) and exposure of breast-fed infants. Methods This was a systematic …
in breast milk (BM) and exposure of breast-fed infants. Methods This was a systematic …
[HTML][HTML] Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Background Globally, more than half of women take medicines whilst breastfeeding. Data
concerning the exposure of the breastfed infant to drugs and any related risks are sparce …
concerning the exposure of the breastfed infant to drugs and any related risks are sparce …
[HTML][HTML] A comprehensive review on non-clinical methods to study transfer of medication into breast milk–A contribution from the ConcePTION project
N Nauwelaerts, N Deferm, A Smits, C Bernardini… - Biomedicine & …, 2021 - Elsevier
Breastfeeding plays a major role in the health and wellbeing of mother and infant. However,
information on the safety of maternal medication during breastfeeding is lacking for most …
information on the safety of maternal medication during breastfeeding is lacking for most …
[HTML][HTML] Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol—a contribution from the ConcePTION project
M Van Neste, N Nauwelaerts, M Ceulemans… - BMJ Paediatrics …, 2024 - ncbi.nlm.nih.gov
Introduction Breastfeeding is beneficial for the health of the mother and child. However, at
least 50% of postpartum women need pharmacotherapy, and this number is rising due to the …
least 50% of postpartum women need pharmacotherapy, and this number is rising due to the …
Emerging research paradigm for infant drug exposure through breast milk
S Ito - Current Pharmaceutical Design, 2019 - ingentaconnect.com
Background: Information on drug secretion into milk is insufficient due to the exclusion of
lactating women from clinical trials and drug development processes. As a result, non …
lactating women from clinical trials and drug development processes. As a result, non …
Determinants of drug transfer into human milk
EJ Begg - Drugs and human lactation, 1996 - Elsevier
Publisher Summary This chapter discusses three major components that affect drug transfer
into human milk and the suckling infant, including maternal pharmacokinetics, mammary …
into human milk and the suckling infant, including maternal pharmacokinetics, mammary …
Safety of medicines during breastfeeding–from case report to modeling: a contribution from the ConcePTION project
E Cardoso, M Guidi, N Nauwelaerts… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Despite many research efforts, current data on the safety of medicines during
breastfeeding are either fragmented or lacking, resulting in restrictive labeling of most …
breastfeeding are either fragmented or lacking, resulting in restrictive labeling of most …
Non-clinical models to determine drug passage into human breast milk
Background: Successful practice of clinical perinatal pharmacology requires a thorough
understanding of the pronounced physiological changes during lactation and how these …
understanding of the pronounced physiological changes during lactation and how these …