High-sensitivity C-reactive protein is a prognostic biomarker of six-month disability after traumatic brain injury: results from the TRACK-TBI study

LB Xu, JK Yue, F Korley, AM Puccio, EL Yuh… - Journal of …, 2021 - liebertpub.com
Systemic inflammation impacts outcome after traumatic brain injury (TBI), but most TBI
biomarker studies have focused on brain-specific proteins. C-reactive protein (CRP) is a …

High-sensitivity C-reactive protein: retrospective study of potential blood biomarker of inflammation in acute mild traumatic brain injury

T Shetty, T Cogsil, A Dalal, E Kim… - The Journal of head …, 2019 - journals.lww.com
Objective: A panel of biomarkers is needed to definitively diagnose mild traumatic brain
injury (mTBI). There is a clear role for the inclusion of an inflammatory biomarker. This study …

Neuroinflammatory biomarkers for traumatic brain injury diagnosis and prognosis: a TRACK-TBI pilot study

JK Yue, FH Kobeissy, S Jain, X Sun… - Neurotrauma …, 2023 - liebertpub.com
The relationship between systemic inflammation and secondary injury in traumatic brain
injury (TBI) is complex. We investigated associations between inflammatory markers and …

Pro-and anti-inflammatory biomarkers and traumatic brain injury outcomes: a review

T Rodney, N Osier, J Gill - Cytokine, 2018 - Elsevier
Abstract Traumatic Brain Injury (TBI) triggers a cascade of secondary biological and
physiological effects that are variable, depending on the severity, location, and complexity of …

Time course of cerebrospinal fluid inflammatory biomarkers and relationship to 6-month neurologic outcome in adult severe traumatic brain injury

EL Nwachuku, AM Puccio, A Adeboye… - Clinical neurology and …, 2016 - Elsevier
Objective Activation of the inflammatory cascade is a known pathophysiologic process in
severe traumatic brain injury (TBI) with yet non-standardized scientific data regarding …

Principal components derived from CSF inflammatory profiles predict outcome in survivors after severe traumatic brain injury

RG Kumar, JE Rubin, RP Berger, PM Kochanek… - Brain, behavior, and …, 2016 - Elsevier
Studies have characterized absolute levels of multiple inflammatory markers as significant
risk factors for poor outcomes after traumatic brain injury (TBI). However, inflammatory …

Inflammatory biomarkers of traumatic brain injury

NH Johnson, R Hadad, RR Taylor, J Rodríguez Pilar… - Pharmaceuticals, 2022 - mdpi.com
Traumatic brain injury (TBI) has a complex pathology in which the initial injury releases
damage associated proteins that exacerbate the neuroinflammatory response during the …

Elevated C-reactive protein levels may be a predictor of persistent unfavourable symptoms in patients with mild traumatic brain injury: a preliminary study

SH Su, W Xu, M Li, L Zhang, YF Wu, F Yu… - Brain, behavior, and …, 2014 - Elsevier
The pathogenesis of persistent unfavourable outcomes following mild traumatic brain injury
(mTBI) are not fully understood. Low-grade systemic inflammation might contribute to the …

[HTML][HTML] Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review

K Visser, M Koggel, J Blaauw, HJ van der Horn… - Neuroscience & …, 2022 - Elsevier
Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …

Early versus late profiles of inflammatory cytokines after mild traumatic brain injury and their association with neuropsychological outcomes

A Vedantam, J Brennan, HS Levin… - Journal of …, 2021 - liebertpub.com
Despite pre-clinical evidence for the role of inflammation in traumatic brain injury (TBI), there
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …