Mesenchymal stem cells genetically engineered to express platelet-derived growth factor and heme oxygenase-1 ameliorate osteoarthritis in a canine model
J Oh, YS Son, WH Kim, OK Kwon, BJ Kang - Journal of Orthopaedic …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are used for the treatment of
osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair …
osteoarthritis (OA), and MSC genetic engineering is expected to enhance cartilage repair …
[HTML][HTML] Intra-articular injection of human synovium-derived mesenchymal stem cells in beagles with surgery-induced osteoarthritis
YS Kim, YI Kim, YG Koh - The Knee, 2021 - Elsevier
Background Recently, cell-based tissue engineering approaches using mesenchymal stem
cells (MSCs) have been used to treat osteoarthritis (OA). However, the efficacy of human …
cells (MSCs) have been used to treat osteoarthritis (OA). However, the efficacy of human …
Human adipose-derived stem cells upregulate IGF-1 and alleviate osteoarthritis in a two-stage rabbit osteoarthritis model
J Wang, S Su, C Dong, Q Fan, J Sun… - Current Stem Cell …, 2024 - benthamdirect.com
Objective: In recent times, it has been recognized that mesenchymal stem cells (MSCs)
possess the capability to address osteoarthritis (OA). The objective of this research was to …
possess the capability to address osteoarthritis (OA). The objective of this research was to …
Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis
Y Qi, G Feng, W Yan - Molecular biology reports, 2012 - Springer
Osteoarthritis (OA) is a common disorder and the restoration of the diseased articular
cartilage in patients with OA is still a challenge for researchers and clinicians. Currently, a …
cartilage in patients with OA is still a challenge for researchers and clinicians. Currently, a …
Clinical-grade human embryonic stem cell-derived mesenchymal stromal cells ameliorate the progression of osteoarthritis in a rat model
D Xing, K Wang, J Wu, Y Zhao, W Liu, JJ Li, T Gao… - Molecules, 2021 - mdpi.com
Mesenchymalstem cell (MSC)-based therapy is being increasingly explored in preclinical
and clinical studies as a regenerative method for treating osteoarthritis (OA). However, the …
and clinical studies as a regenerative method for treating osteoarthritis (OA). However, the …
Human adipose-derived mesenchymal progenitor cells engraft into rabbit articular cartilage
W Wang, N He, C Feng, V Liu, L Zhang… - International Journal of …, 2015 - mdpi.com
Mesenchymal stem cells (MSCs) are known to have the potential for articular cartilage
regeneration, and are suggested for the treatment of osteoarthritis (OA). Here, we …
regeneration, and are suggested for the treatment of osteoarthritis (OA). Here, we …
Mesenchymal stem cells and their clinical applications in osteoarthritis
YH Chang, HW Liu, KC Wu, DC Ding - Cell transplantation, 2016 - journals.sagepub.com
Osteoarthritis is a chronic degenerative joint disorder characterized by articular cartilage
destruction and osteophyte formation. Chondrocytes in the matrix have a relatively slow …
destruction and osteophyte formation. Chondrocytes in the matrix have a relatively slow …
[HTML][HTML] Allogeneic mesenchymal stem cells in combination with hyaluronic acid for the treatment of osteoarthritis in rabbits
ER Chiang, HL Ma, JP Wang, CL Liu, TH Chen… - PloS one, 2016 - journals.plos.org
Mesenchymal stem cell (MSC)-based therapies may aid in the repair of articular cartilage
defects. The purpose of this study was to investigate the effects of intraarticular injection of …
defects. The purpose of this study was to investigate the effects of intraarticular injection of …
Can mesenchymal stem cells and their conditioned medium assist inflammatory chondrocytes recovery?
YC Chen, YW Chang, KP Tan, YS Shen, YH Wang… - PloS one, 2018 - journals.plos.org
Osteoarthritis (OA), one of the most common joint disease, affects more than 80% of the
population aged 70 or over. Mesenchymal stem cells (MSCs) show multi-potent …
population aged 70 or over. Mesenchymal stem cells (MSCs) show multi-potent …
Mixed cell therapy of bone marrow-derived mesenchymal stem cells and articular cartilage chondrocytes ameliorates osteoarthritis development
I Prasadam, A Akuien, TE Friis, W Fang, X Mao… - Laboratory …, 2018 - nature.com
Of the many cell-based treatments that have been tested in an effort to regenerate
osteoarthritic articular cartilage, none have ever produced cartilage that compare with native …
osteoarthritic articular cartilage, none have ever produced cartilage that compare with native …