The risk of Alzheimer's disease (AD) is higher in women than in men, a sex difference that
likely results from the effects of sex steroid hormones. To investigate this relationship, we first …

Epidemiological studies indicate that women have a higher risk of Alzheimer's disease (AD)
even after adjustment for age. Though transgenic mouse models of AD develop AD-related …

Female sex is a leading risk factor for developing Alzheimer's disease (AD). Sexual
dimorphism in AD is gaining attention as clinical data show that women are not only more …

Estrogen depletion in postmenopausal women is a significant risk factor for the development
of Alzheimer's disease (AD), and estrogen-based hormone therapy may reduce this risk …

Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Background Several transgenic animal models genetically predisposed to develop
Alzheimer's disease (AD)-like pathology have been engineered to facilitate the study of …

Normal age-related testosterone depletion in men is a recently identified risk factor for
Alzheimer's disease (AD), but how androgen loss affects the development of AD is unclear …

We sought to determine if sex impacts the cognitive and neuropathological phenotype of the
3xTg-AD mice. We find that male and female 3xTg-AD mice show comparable impairments …

Background Alzheimer's disease (AD) is notably associated with cognitive decline resulting
from impaired function of hippocampal and cortical areas; however, several other domains …

Alzheimer's disease is a progressive neurodegenerative disorder and the most common
form of dementia. Like many neurological disorders, Alzheimer's disease has a sex‐biased …