Stiffness and topography of biomaterials dictate cell‐matrix interaction in musculoskeletal cells at the bio‐interface: a concise progress review

M Bai, L Cai, X Li, L Ye, J Xie - Journal of Biomedical Materials …, 2020 - Wiley Online Library
Mutually interacted musculoskeletal tissues work together within the physiological
environment full of varieties of external stimulus. Consistent with the locomotive function of …

[HTML][HTML] Cellular modulation by the mechanical cues from biomaterials for tissue engineering

Q Wei, S Wang, F Han, H Wang, W Zhang… - Biomaterials …, 2021 - ncbi.nlm.nih.gov
Mechanical cues from the extracellular matrix (ECM) microenvironment are known to be
significant in modulating the fate of stem cells to guide developmental processes and …

Biomaterial stiffness guides cross-talk between chondrocytes: implications for a novel cellular response in cartilage tissue engineering

L Cai, W Liu, Y Cui, Y Liu, W Du, L Zheng… - ACS Biomaterials …, 2020 - ACS Publications
The exquisite cartilage architecture maintains an orderly dynamic equilibrium as a result of
the interplay between chondrocyte functions and the unique extracellular matrix (ECM) …

Mechanophysical cues in extracellular matrix regulation of cell behavior

T Wang, SS Nanda, GC Papaefthymiou… - ChemBioChem, 2020 - Wiley Online Library
The extracellular matrix (ECM) is a macromolecular network that can provide biochemical
and structural support for cell adhesion and formation. It regulates cell behavior by …

Cellular modulation by the elasticity of biomaterials

F Han, C Zhu, Q Guo, H Yang, B Li - Journal of Materials Chemistry B, 2016 - pubs.rsc.org
The behaviors and functions of individual cells, fundamental to the complexity of
multicellular organisms, are regulated by their integrated response to a variety of …

Mechanobiology-informed biomaterial and tissue engineering strategies for influencing skeletal stem and progenitor cell fate

SM Woodbury, WB Swanson, Y Mishina - Frontiers in Physiology, 2023 - frontiersin.org
Skeletal stem and progenitor cells (SSPCs) are the multi-potent, self-renewing cell lineages
that form the hematopoietic environment and adventitial structures of the skeletal tissues …

Extracellular matrix elasticity and topography: Material‐based cues that affect cell function via conserved mechanisms

IA Janson, AJ Putnam - … of biomedical materials research Part A, 2015 - Wiley Online Library
Chemical, mechanical, and topographic extracellular matrix (ECM) cues have been
extensively studied for their influence on cell behavior. These ECM cues alter cell adhesion …

Manipulation of stem cells fates: the master and multifaceted roles of biophysical cues of biomaterials

X Wan, Z Liu, L Li - Advanced Functional Materials, 2021 - Wiley Online Library
Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …

Intrinsic extracellular matrix properties regulate stem cell differentiation

GC Reilly, AJ Engler - Journal of biomechanics, 2010 - Elsevier
One of the recent paradigm shifts in stem cell biology has been the discovery that stem cells
can begin to differentiate into mature tissue cells when exposed to intrinsic properties of the …

Cell–extracellular matrix mechanobiology: forceful tools and emerging needs for basic and translational research

AW Holle, JL Young, KJ Van Vliet, RD Kamm… - Nano …, 2018 - ACS Publications
Extracellular biophysical cues have a profound influence on a wide range of cell behaviors,
including growth, motility, differentiation, apoptosis, gene expression, adhesion, and signal …