Background. Studying malaria parasites cross resistance to sulfadoxine-pyrimethamine (SP)
and trimethoprim-sulfamethoxazole (cotrimoxazole, CTX) is necessary in areas coendemic …

Abstract Background In 2005, the Democratic Republic of the Congo (DRC) switched to
artesunate/amodiaquine as the first-line antimalarial in response to increasing sulfadoxine …

Malaria poses public health threats worldwide. Nigeria accounted for the highest numbers of
cases (26.8%) and deaths (31.9%) among countries where malaria is endemic in 2020 …

Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs.
Monitoring molecular markers in exported malaria infections provides an efficient way to …

Background Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of
uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed …

Background Despite significant progress in eliminating malaria from the Kingdom of Saudi
Arabia, the disease is still endemic in the southwestern region of the country. Artesunate …

Background Anti-malarial drug resistance is a severe challenge for eventual control and
global elimination of malaria. Resistance to sulfadoxine-pyrimethamine (SP) increases as …

A major challenge in the fight to effectively control malaria is the emergence of resistant
parasite to drugs used in therapy as well as for chemoprevention. In this study, single …

The spread of anti-malarial drug resistance will challenge any malaria control and
elimination strategies, and routine monitoring of resistance-associated molecular markers of …

The main objective of this investigation was whether the combination therapy of sulfadoxine
pyrimethamine (SP) plus artesunate (AS) protects against the spread of resistance to SP in …