Background: Little research has explored the detail of practice when using sedative
medications at the end of life. One work package of the I-CAN-CARE research programme …

Sedation at the end of life can be ethically contentious and is often bedevilled by lack of
clarity about definitions. There has been controversy1 over the increasing use of 'continuous …

Background: Palliative sedation, or bringing about a state of decreased or absent
awareness (unconsciousness), is one of the therapies used in end-of-life healthcare settings …

The administration of sedative drugs at the end of life raises both clinical and ethical
challenges. This article details the evolution of sedation decision-making practices at a 14 …

After more than 15 years of engagement in research on palliative sedation, we dare to pose
that it is among the most challenging topics in end-of-life care. The first publications on …

Background: Sedatives are frequently used towards the end of life. However, there is scarce
information when their use is labelled as 'palliative sedation'. Aim: To assess the use and …

Background: Evidence exists for the use of palliative sedation for people approaching the
last days of life with refractory and intolerable symptoms. It is a third-line intervention that …

Abstract Objective In Switzerland, palliative sedation consists of using sedatives to relieve
terminally ill patients. It is divided into several steps, with one of them consisting of informing …

Background A significant minority of dying people experience refractory symptoms or
extreme distress unresponsive to conventional therapies. In such circumstances, sedation …

Context: Patients nearing the end of life may experience symptoms that are refractory to
standard therapeutic options. Physicians may consider palliative sedation to relieve …