Schizophrenia has substantial variation in symptom severity, course of illness, and overall
functioning. Earlier age of onset (AOO) is consistently associated with negative outcomes …

Schizophrenia is a heritable neurocognitive disorder affecting about 1% of the population,
and usually has an onset age at around 21–25 in males and 25–30 in females. Recent …

Schizophrenia is a genetically and clinically heterogeneous disorder. Genetic risk factors for
the disorder may differ between the sexes or between multiply affected families compared to …

In schizophrenia, clinical, familial and biological characteristics according to age at onset
(AAO) suggest that AAO is a valid candidate symptom for genetic studies. However, none of …

This chapter characterises the age of onset (AOO) of schizophrenia spectrum disorders and
summarises findings regarding a range of clinical and social outcomes, cognition, brain …

An earlier age at onset (AAO) has been associated with greater genetic loadings in
schizophrenia. This study aimed to identify modifier loci associated with an earlier AAO of …

Schizophrenia is a genetically complex illness with heterogeneous clinical presentation,
including variable age of onset. In this study, the heritability, or proportion of variation in age …

Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early
adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease …

The children of older fathers have increased risks of developing schizophrenia spectrum
disorders, and among those who develop these disorders, those with older fathers present …

One of the most consistent findings in the epidemiology of schizophrenia is that males are
younger at the onset of schizophrenia than females. However, the vast majority of studies …