OBJECTIVE The long-term impact of intentional weight loss on cardiovascular events
remains unknown. We describe 12-month changes in body weight and cardiovascular risk …

Importance Strategies targeting body composition may help prevent chronic diseases in
persons with excess weight, but randomized clinical trials evaluating lifestyle interventions …

Background The development and implementation of effective physical activity (PA)
intervention programs is challenging, particularly in older adults. After the first year of the …

Importance High-quality dietary patterns may help prevent chronic disease, but limited data
exist from randomized trials about the effects of nutritional and behavioral interventions on …

Background: Little evidence exists on the effect of an energy-unrestricted healthy diet on
metabolic syndrome. We evaluated the long-term effect of Mediterranean diets ad libitum on …

Background Epidemiological studies suggest that the Mediterranean diet (MedDiet) may
reduce the risk of developing the metabolic syndrome (MetS). We compared the 1-year …

Metabolic syndrome (MS) is a cluster of metabolic alteration associated with a higher risk of
cardiovascular disease and overall mortality than the single alterations alone. The Italian …

Introduction and objectives The cardiovascular benefits of the Mediterranean diet have
usually been assessed under assumptions of ad libitum total energy intake (ie, no energy …

Objective Independently of total caloric intake, a better quality of the diet (for example,
conformity to the Mediterranean diet) is associated with lower obesity risk. It is unclear …

BACKGROUND Intensive lifestyle intervention significantly reduces the progression to
diabetes in high-risk individuals. OBJECTIVE It is not known whether a program of moderate …