1, 25 (OH) 2D3 regulates calcium homeostasis through its actions in the intestine, bone, and
kidney. These actions are mediated through the VDR. To determine if VDR's actions in the …

Intestinal calcium (Ca) absorption depends upon vitamin D signaling through the vitamin D
receptor (VDR) in the proximal and distal intestine while lower VDR content causes …

Although the intestine plays the major role in 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3]
action on calcium homeostasis, the mechanisms involved remain incompletely understood …

The active form of vitamin D, 1, 25 (OH) 2 D, is a crucial regulator of calcium homeostasis,
especially through stimulation of intestinal calcium transport. Lack of intestinal vitamin D …

Dihydroxyvitamin D3 (1, 25 (OH) 2D3)-mediated intestinal calcium (Ca) absorption supplies
Ca for proper bone mineralization during growth. We tested whether vitamin D receptor …

BACKGROUND & AIMS: Vitamin D receptor (VDR)-knockout mice develop severe
hypocalcemia and rickets, accompanied by disruption of active intestinal calcium absorption …

We tested the hypothesis that low vitamin D receptor (VDR) level causes intestinal vitamin D
resistance and intestinal calcium (Ca) malabsorption. To do so, we examined vitamin D …

The vitamin D endocrine system is essential for calcium and bone homeostasis. The precise
mode of action and the full spectrum of activities of the vitamin D hormone, 1, 25 …

The serum calcium levels and the calcium content of the skeleton are highly interdependent.
Indeed, bone requires calcium to preserve its strength, but it is at the same time also the …

The physiological and beneficial actions of vitamin D in bone health have been
experimentally and clinically proven in mammals. The active form of vitamin D [1α, 25 (OH) …