ALS is a relentlessly progressive and fatal disease, with no curative therapies available to
date. Symptomatic and palliative care, provided in a multidisciplinary context, still remains …

Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease is the most common motor
neuron disease in human adults, described as early as 1869 by a French neurobiologist and …

Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) characterized by
the death of upper and lower motor neurons (corticospinal tract) in the motor cortex, basal …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, adult-onset neurodegenerative
disease characterized by selective dysfunction and death of motor neurons in the brain and …

With the acceleration in our understanding of ALS and the related motor neuron disease has
come even greater challenges in reconciling all of the proposed pathogenic mechanisms …

Since the approval of riluzole for the treatment of amyotrophic lateral sclerosis (ALS) 17
years ago, more than 30 large clinical trials have been conducted, but none has proved …

Recent years have witnessed a renewed interest in the pathogenic mechanisms of
amyotrophic lateral sclerosis (ALS), a late-onset progressive degeneration of motor neurons …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …

Purpose Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …