Autologous dendritic cells pulsed with lysate from an allogeneic hepatic cancer cell line as a treatment for patients with advanced hepatocellular carcinoma: a pilot …

MTA Ghafar, MA Morad, EA El-Zamarany… - International …, 2020 - Elsevier
Objectives This is a randomized trial adopted to evaluate the safety and efficacy of
immunization with specific anti-hepatocellular carcinoma dendritic cells (DCs) in Egyptian …

Immunotherapy by autologous dendritic cell vaccine in patients with advanced HCC

M El Ansary, S Mogawer, SA Elhamid, S Alwakil… - Journal of cancer …, 2013 - Springer
Abstract Background Dendritic cells (DCs) could be used as potential cellular adjuvant for
the production of specific tumor vaccines. Objectives Our study was aimed to evaluate the …

[PDF][PDF] A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma

DH Palmer, RS Midgley, N Mirza, EE Torr… - …, 2009 - Wiley Online Library
This is a phase II clinical trial investigating the safety and efficacy of intravenous vaccination
with mature autologous dendritic cells (DCs) pulsed ex vivo with a liver tumor cell line lysate …

Vaccination of advanced hepatocellular carcinoma patients with tumor lysate-pulsed dendritic cells: a clinical trial

WC Lee, HC Wang, CF Hung, PF Huang… - Journal of …, 2005 - journals.lww.com
Hepatocellular carcinoma (HCC) is a common and rapidly progressing malignancy. Current
treatment options for advanced HCC are limited. This clinical study of dendritic cell (DC) …

A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer

Y Iwashita, K Tahara, S Goto, A Sasaki, S Kai… - Cancer Immunology …, 2003 - Springer
Background/aims To evaluate the safety and feasibility of immunotherapy based on
autologous dendritic cells (DC) for patients with unresectable primary liver cancer (PLC) …

[HTML][HTML] Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma

F Tada, M Abe, M Hirooka, Y Ikeda… - International …, 2012 - spandidos-publications.com
Dendritic cells (DCs) are increasingly used as adjuvants for vaccination strategies; however,
there has been very little development in DC vaccines for patients with hepatocellular …

Adjuvant immunotherapy with autologous dendritic cells for hepatocellular carcinoma, randomized phase II study

JH Lee, WY Tak, Y Lee, MK Heo, JS Song… - …, 2017 - Taylor & Francis
Our previous phase I/IIA study showed that autologous dendritic cells (DCs) pulsed with
tumor-associated antigens are well tolerated in patients with hepatocellular carcinoma …

A phase I/IIa study of adjuvant immunotherapy with tumour antigen-pulsed dendritic cells in patients with hepatocellular carcinoma

JH Lee, Y Lee, M Lee, MK Heo, JS Song… - British journal of …, 2015 - nature.com
Background: To date, no adjuvant treatment has been shown to have a clear benefit in
patients with hepatocellular carcinoma (HCC). In this prospective phase I/IIa study, we …

[PDF][PDF] Dendritic cell as therapeutic vaccines against tumors and its role in therapy for hepatocellular carcinoma

K Sun, L Wang, Y Zhang - Cell Mol Immunol, 2006 - Citeseer
Dendritic cells (DCs) are the most potent professional antigen-presenting cells, and capable
of stimulating naïve T cells and driving primary immune responses. DCs are poised to …

[HTML][HTML] Immunotherapy of patient with hepatocellular carcinoma using cytotoxic T lymphocytes ex vivo activated with tumor antigen-pulsed dendritic cells

Y Wang, X Yang, Y Yu, Z Xu, Y Sun, H Liu… - Journal of …, 2018 - ncbi.nlm.nih.gov
Purpose The aim of this study was to evaluate the clinical response of immunotherapy with
dendritic cell-cytotoxic T lymphocytes (DC-CTLs) in patients with hepatocellular carcinoma …