Dual-specificity protein phosphatase 5 (DUSP5) is a member of the tyrosine-threonine
phosphatase family with the ability to dephosphorylate and inactivate extracellular signal …

We recently reported that KO of Dual‐specificity protein phosphatase 5 (Dusp5) enhances
myogenic reactivity and blood flow autoregulation in the cerebral and renal circulations in …

Abstract Dual-specificity phosphatase 26 (DUSP26) acts as a pivotal player in the
transduction of signalling cascades with its dephosphorylating activity. Currently, DUSP26 …

Abstract Aim Dual Specificity Phosphatase 3 (DUSP3) regulates the innate immune
response, with a putative role in angiogenesis. Modulating inflammation and perfusion …

Abstract Dual specificity phosphatase 22 (DUSP22) regulates fibrosis and inflammation,
which may be implicated in the development of diabetic nephropathy (DN). Hence, the …

We recently reported that the myogenic responses of the renal afferent arteriole (Af-Art) and
middle cerebral artery (MCA) and autoregulation of renal and cerebral blood flow (RBF and …

Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) are
neurodegenerative disorders. Recent studies suggest that cerebral hypoperfusion is an …

In response to injury, vascular smooth muscle cells (VSMCs) of the arterial wall
dedifferentiate into a proliferative and migratory phenotype, leading to intimal hyperplasia …

Pathological cardiac hypertrophy is an independent risk factor of heart failure. However, we
still lack effective methods to reverse cardiac hypertrophy. DUSP12 is a member of the dual …

Abstract Dual-specificity phosphatase 14 (Dusp14), an important negative modulator of
mitogen-activated protein kinase (MAPK) signaling pathways, has been implicated in …