Optimization of cloned enzyme donor immunoassay cut-offs for drugs of abuse in whole blood of drivers involved in road accidents

G Pelletti, M Garagnani, F Rossi, R Roffi… - Forensic science …, 2019 - Elsevier
Introduction Immunoassay (IA) tests should be able to detect low concentrations of illegal
drugs when used for the screening of drugs in drivers. False negatives should be avoided …

Optimization of cloned enzyme donor immunoassay cut-offs for drugs of abuse in post-mortem whole blood

G Pelletti, F Rossi, M Garagnani, R Barone… - Forensic science …, 2020 - Elsevier
Introduction Immunoassay (IA) tests are not widely applied in post-mortem samples, since
they are based on technologies requiring relatively non-viscous specimens, and compounds …

Optimization and validation of CEDIA drugs of abuse immunoassay tests in serum and urine on an Olympus AU 400

F Musshoff, T Wolters, S Lott, J Ippisch… - Drug testing and …, 2013 - Wiley Online Library
A preliminary initial cloned enzyme donor immunoassay (CEDIA) was optimized for serum
and urine drug testing with respect to the German per se limits for driving under the influence …

Optimization and validation of CEDIA drugs of abuse immunoassay tests in serum on Hitachi 912

KM Kirschbaum, F Musshoff, R Schmithausen… - Forensic science …, 2011 - Elsevier
Due to sensitive limits of detection of chromatographic methods and low limit values
regarding the screening of drugs under the terms of impairment in safe driving (§ 24a StVG …

Validation of an automated microplate enzyme immunoassay for screening of postmortem blood for drugs of abuse

VR Spiehler, IB Collison, PR Sedgwick… - Journal of analytical …, 1998 - academic.oup.com
The objective of this study was to compare the sensitivity and specificity of an enzyme
immunoassay employing antibodies bound to a microtiter plate (MPEIA) with those of two …

Cloned enzyme donor immunoassay (CEDIA) for drugs-of-abuse screening

DA Armbruster, EC Hubster, MS Kaufman… - Clinical …, 1995 - academic.oup.com
Abstract Large numbers of specimens (5000-18,000) were screened for amphetamines,
barbiturates, cocaine, marijuana, opiates, and phencyclidine by RIA (Roche), Emit II (Syva) …

Comparison of several immunoassays used in drugs of abuse screening: Assessment against gold standard methods and calculation of measurement uncertainty

A Mina - Journal of pharmacological and toxicological methods, 2020 - Elsevier
Background Immunoassays provide simple, powerful and inexpensive screening methods
for urine drug screening. Other substances and/or factors may interfere with the test and …

Evaluation of immunoassay methods for the screening of cocaine metabolites in urine

LD Baugh, E Ellen Allen, RH Liu… - Journal of …, 1991 - asmedigitalcollection.asme.org
Immunoassay kits for urine cocaine (and metabolite) screening, obtained from two
commercial sources, were examined for correlation of their results, expressed in terms of …

Comprehensive toxicological screening of common drugs of abuse, new psychoactive substances and cannabinoids in blood using supported liquid extraction and …

J Ayala, S Kerrigan - Journal of analytical toxicology, 2023 - academic.oup.com
Immunoassay (IA) is currently the most widely used technique for toxicological screening in
drug-impaired driving investigations. However, practical limitations in the scope of testing …

Performance of immunoassays in screening for opiates, cannabinoids and amphetamines in post-mortem blood

Y Hino, I Ojanperä, I Rasanen, E Vuori - Forensic science international, 2003 - Elsevier
Several immunoassay methods for screening of abused drugs in whole blood were
evaluated in post-mortem forensic toxicology. Blood samples known to be positive or …