[PDF][PDF] RP-HPLC method development for quantitation of valsartan in nano-structured lipid carrier formulation and in vitro release studies
O Al Wassil, ME Omer, AEB Yassin… - Dig J Nanomater …, 2020 - chalcogen.ro
Valsartan (Val) is angiotensin II receptor blocker used in the treatment of congestive heart
failure, high blood pressure and post-myocardial infarction [1-4]. Val acts on receptor …
failure, high blood pressure and post-myocardial infarction [1-4]. Val acts on receptor …
Formulation development and evaluation of lipid based nanoparticles of valsartan by microemulsification
Valsartan is an antihypertensive drug with poor oral bioavailability ranging from 10-35%
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
Pharmacokinetic Evaluation of Improved Oral Bioavailability of Valsartan: Proliposomes Versus Self-Nanoemulsifying Drug Delivery System
V Nekkanti, Z Wang, GV Betageri - AAPS PharmSciTech, 2016 - Springer
The objective of this study was to develop proliposomes and self-nanoemulsifying drug
delivery system (SNEDDS) for a poorly bioavailable drug, valsartan, and to compare their in …
delivery system (SNEDDS) for a poorly bioavailable drug, valsartan, and to compare their in …
[PDF][PDF] Formulation optimization and evaluation of nanostructured lipid carriers containing valsartan
RJ Patel, ZP Patel - International journal of pharmaceutical …, 2013 - researchgate.net
Nanostructured lipid carriers (NLCs), a lipid based colloidal carrier system, offer many
advantages such as increase the solubility, improves the bioavailability and therapeutic …
advantages such as increase the solubility, improves the bioavailability and therapeutic …
[PDF][PDF] Valsartan loaded solid lipid nanoparticles: development, characterization and in vitro and ex vivo evaluation
B Parmar, S Mandal, KC Petkar, LD Patel… - Int J Pharm Sci …, 2011 - researchgate.net
Valsartan is an antihypertensive drug with poor oral bioavailability ranging from 10-35%
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
because of poor solubility, dissolution and most importantly, extensive first pass hepatic …
Formulation and evaluation of Valsartan solid lipid nanoparticles
M Chandana, MV Ramana, NR Rao - Journal of Drug Delivery and …, 2021 - jddtonline.info
Valsartan is a potent and specific competitive angiotensin II antagonist which is used in the
management of hypertension. It is well absorbed following oral administration, with rather …
management of hypertension. It is well absorbed following oral administration, with rather …
Development and characterization of a novel nanosuspension based drug delivery system of valsartan: A poorly soluble drug
S Vidyadhara - Asian Journal of Pharmaceutics (AJP), 2015 - asiapharmaceutics.info
The purpose of the present study was to formulate valsartan nanosuspension to increase the
aqueous solubility and to improve its oral bioavailability. Valsartan is a poorly water†…
aqueous solubility and to improve its oral bioavailability. Valsartan is a poorly water†…
Preparation and evaluation of a lipid-based drug delivery system to ımprove valsartan oral bioavailability: pharmacokinetic and pharmacodynamic analysis
E Gülmezoğlu, G Yıldız Türkyılmaz… - Drug Development and …, 2022 - Taylor & Francis
Antihypertensive treatment reduces the risk of cardiovascular complications in patients with
high mortality with hypertension. Valsartan is highly selective antihypertensive that is rapidly …
high mortality with hypertension. Valsartan is highly selective antihypertensive that is rapidly …
Preparation and in vitro characterization of valsartan-loaded ethyl cellulose and poly (methyl methacrylate) nanoparticles
E Hajba-Horváth, E Biró, M Mirankó, A Fodor-Kardos… - RSC …, 2020 - pubs.rsc.org
Valsartan is an antihypertensive drug used primarily orally, however, due to its hydrophobic
nature it has got low bio-availability thus requiring higher dosage/frequency and causing …
nature it has got low bio-availability thus requiring higher dosage/frequency and causing …
[PDF][PDF] Formulation, in-vitro evaluation and optimization of valsartan nano-lipid complex by Box-Behnken design
MI Mohamed, HA Mahmoud, AI Mohamed… - Pak. J. Pharm …, 2023 - researchgate.net
The antihypertensive drug valsartan, has an imperfect bioavailability due to its low solubility,
permeability and excessive first pass hepatic metabolism. So, the goal of this article is to …
permeability and excessive first pass hepatic metabolism. So, the goal of this article is to …