Binge eating in humans is driven by hedonic properties of food, suggesting that brain reward
systems may contribute to this behaviour. We examined the role of mu opioid receptors …

Rationale Evidence suggests that the palatability of food (ie, the hedonic impact produced
by its sensory features) can promote feeding and may underlie compulsive eating, leading to …

Binge eating, a central feature of multiple eating disorders, is characterized by excessive
consumption occurring during discrete, often brief, intervals. Highly palatable foods play an …

Binge eating disorder is the most common eating disorder, but its underlying etiology is
poorly understood. Both humans and animals exhibit binge-like intake of highly-palatable …

Endogenous opioids within the central nervous system are postulated to mediate hedonic
aspects of feeding behavior. To identify the relevant endogenous opioid receptor ligands …

Altered motivational processes might participate to the physiopathology of eating‐related
disorders. The endogenous opioid system is thought to mediate the hedonic properties of …

Endogenous opioids are involved in the hedonic aspects of eating. Opioid impairments and
alterations have been implicated in the pathophysiology of bulimia nervosa and binge …

Food reward can be driven by separable mechanisms of hedonic impact (food 'liking') and
incentive motivation (food 'wanting'). Brain mu-opioid systems contribute crucially to both …

Endogenous opioids, and in particular μ-opioid receptors, have been linked to hedonic and
rewarding mechanisms engaged during palatable food intake. The aim of this study was to …

Central administration of general and selective opioid receptor subtype antagonists in the rat
has revealed a substantial role for μ, a moderate role for κ, and a minimal role for δ receptors …