Development of Bioinformatics Software Tools for Network-and Pathway-Based Exploration of miRNA Target Interactions

S Haunsberger - 2022 - repository.rcsi.com
miRNAs are short, non-coding RNA involved in the post-transcriptional regulation of mRNA
in both health and disease. A single miRNA can target hundreds or even thousands of …

PRIMITI: a computational approach for accurate prediction of miRNA-target mRNA interaction

K Uthayopas, AGC de S, A Alavi, DEV Pires, DB Ascher - bioRxiv, 2024 - biorxiv.org
Current medical research has been demonstrating the roles of miRNAs in a variety of
cellular mechanisms, lending credence to the association between miRNA dysregulation …

miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions

SD Hsu, YT Tseng, S Shrestha, YL Lin… - Nucleic acids …, 2014 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively
regulating gene expression to control many cellular mechanisms. The miRTarBase …

[HTML][HTML] Experimental procedures to identify and validate specific mRNA targets of miRNAs

TS Elton, JC Yalowich - EXCLI journal, 2015 - ncbi.nlm.nih.gov
Functionally matured microRNAs (miRNAs) are small single-stranded non-coding RNA
molecules which are emerging as important post-transcriptional regulators of gene …

Computational resources for analysis of miRNA targetome

A Thakur, S Kamboj, M Kumar - MicroRNA in Human Malignancies, 2022 - Elsevier
Abstract microRNA is a small RNA molecule that controls gene expression at the
posttranscriptional level. It can regulate the expression of one or more target mRNAs. Owing …

mintRULS: Prediction of miRNA–mRNA Target Site Interactions Using Regularized Least Square Method

S Shakyawar, S Southekal, C Guda - Genes, 2022 - mdpi.com
Identification of miRNA–mRNA interactions is critical to understand the new paradigms in
gene regulation. Existing methods show suboptimal performance owing to inappropriate …

MicroRNA target prediction and validation

G Thillaiyampalam, AS Cristino - MicroRNA, 2022 - Elsevier
MicroRNAs (miRNAs) are an evolutionarily conserved component of gene regulatory
networks and essential for the development and maintenance of all multicellular organisms …

miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions

HY Huang, YCD Lin, S Cui, Y Huang… - Nucleic acids …, 2022 - academic.oup.com
MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target
mRNAs to regulate gene expression and produce significant changes in various …

miRTar: an integrated system for identifying miRNA-target interactions in human

JBK Hsu, CM Chiu, SD Hsu, WY Huang, CH Chien… - BMC …, 2011 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNA molecules that are~ 22-nt-
long sequences capable of suppressing protein synthesis. Previous research has suggested …

Combining results from distinct microRNA target prediction tools enhances the performance of analyses

AC Oliveira, LA Bovolenta, PG Nachtigall… - Frontiers in …, 2017 - frontiersin.org
Target prediction is generally the first step toward recognition of bona fide microRNA
(miRNA)-target interactions in living cells. Several target prediction tools are now available …