Development of Bioinformatics Software Tools for Network-and Pathway-Based Exploration of miRNA Target Interactions
S Haunsberger - 2022 - repository.rcsi.com
miRNAs are short, non-coding RNA involved in the post-transcriptional regulation of mRNA
in both health and disease. A single miRNA can target hundreds or even thousands of …
in both health and disease. A single miRNA can target hundreds or even thousands of …
PRIMITI: a computational approach for accurate prediction of miRNA-target mRNA interaction
Current medical research has been demonstrating the roles of miRNAs in a variety of
cellular mechanisms, lending credence to the association between miRNA dysregulation …
cellular mechanisms, lending credence to the association between miRNA dysregulation …
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions
MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively
regulating gene expression to control many cellular mechanisms. The miRTarBase …
regulating gene expression to control many cellular mechanisms. The miRTarBase …
[HTML][HTML] Experimental procedures to identify and validate specific mRNA targets of miRNAs
TS Elton, JC Yalowich - EXCLI journal, 2015 - ncbi.nlm.nih.gov
Functionally matured microRNAs (miRNAs) are small single-stranded non-coding RNA
molecules which are emerging as important post-transcriptional regulators of gene …
molecules which are emerging as important post-transcriptional regulators of gene …
Computational resources for analysis of miRNA targetome
Abstract microRNA is a small RNA molecule that controls gene expression at the
posttranscriptional level. It can regulate the expression of one or more target mRNAs. Owing …
posttranscriptional level. It can regulate the expression of one or more target mRNAs. Owing …
mintRULS: Prediction of miRNA–mRNA Target Site Interactions Using Regularized Least Square Method
Identification of miRNA–mRNA interactions is critical to understand the new paradigms in
gene regulation. Existing methods show suboptimal performance owing to inappropriate …
gene regulation. Existing methods show suboptimal performance owing to inappropriate …
MicroRNA target prediction and validation
G Thillaiyampalam, AS Cristino - MicroRNA, 2022 - Elsevier
MicroRNAs (miRNAs) are an evolutionarily conserved component of gene regulatory
networks and essential for the development and maintenance of all multicellular organisms …
networks and essential for the development and maintenance of all multicellular organisms …
miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions
MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target
mRNAs to regulate gene expression and produce significant changes in various …
mRNAs to regulate gene expression and produce significant changes in various …
miRTar: an integrated system for identifying miRNA-target interactions in human
JBK Hsu, CM Chiu, SD Hsu, WY Huang, CH Chien… - BMC …, 2011 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNA molecules that are~ 22-nt-
long sequences capable of suppressing protein synthesis. Previous research has suggested …
long sequences capable of suppressing protein synthesis. Previous research has suggested …
Combining results from distinct microRNA target prediction tools enhances the performance of analyses
Target prediction is generally the first step toward recognition of bona fide microRNA
(miRNA)-target interactions in living cells. Several target prediction tools are now available …
(miRNA)-target interactions in living cells. Several target prediction tools are now available …