[PDF][PDF] Development of a prognostic signature for esophageal cancer based on a novel 7-DNA damage repair genes signature

J Zhan, W Wang, Y Tang, N Zhou, D Jiang - Biocell, 2022 - cdn.techscience.cn
Esophageal cancer (EC) was an aggressive malignant neoplasm characterized by high
morbidity and poor prognosis. Identifying the changes in DNA damage repair genes helps to …

[HTML][HTML] A novel DNA damage repair gene-related prognostic model for evaluating the prognosis and tumor microenvironment infiltration of esophageal squamous cell …

D Guo, X Zhang, X Du, W Yao, W Shen, S Zhu - BMC Medical Genomics, 2023 - Springer
Background This study aimed to investigate the potential prognostic value of DNA damage
repair genes (DDRGs) in esophageal squamous cell carcinoma (ESCC) and their …

[HTML][HTML] Development and validation of a DNA repair gene signature for prognosis prediction in Colon Cancer

X Wang, C Tan, M Ye, X Wang, W Weng… - Journal of …, 2020 - ncbi.nlm.nih.gov
Aberrant expression of DNA repair genes (DRGs) can be related to tumor progression and
clinical outcomes in colon cancer. Here, we aimed to establish a DRGs signature to identify …

[HTML][HTML] Identification of DNA repair-related genes predicting pathogenesis and prognosis for liver cancer

W Zhu, Q Zhang, M Liu, M Yan, X Chu, Y Li - Cancer cell international, 2021 - Springer
Background Liver cancer (LC) is one of the most fatal cancers throughout the world. More
efficient and sensitive gene signatures that could accurately predict survival in LC patients …

Novel DNA damage repair signature for immunotherapy and a proposed molecular subtyping scheme in gastric cancer

X Li, C Wang, H Dong, J Chen, S Chen, M Li, H Chen… - 2024 - researchsquare.com
The DNA damage repair (DDR) mechanisms is closely related to the occurrence and
progression of cancer cells. The diversity and complexity of DNA repair mechanisms also …

[HTML][HTML] Identification and validation of prognosis-associated DNA repair gene signatures in colorectal cancer

D Song, D Zhang, S Chen, J Wu, Q Hao, L Zhao… - Scientific Reports, 2022 - nature.com
Colorectal cancer (CRC) is the third most common malignant tumor. DNA damage plays a
crucial role in tumorigenesis, and abnormal DNA repair pathways affect the occurrence and …

Identification of a Ten‐Gene Signature of DNA Damage Response Pathways with Prognostic Value in Esophageal Squamous Cell Carcinoma

W Zhuang, X Ben, Z Zhou, Y Ding, Y Tang… - Journal of …, 2021 - Wiley Online Library
Molecular prognostic signatures are critical for treatment decision‐making in esophageal
squamous cell cancer (ESCC), but the robustness of these signatures is limited. The …

DNA damage repair-related gene signature can influence immune status and predict prognosis in hepatocellular carcinoma

Y Lu, S Wang, T Chi, Y Zhao, H Guo, H Wang, L Feng - 2023 - researchsquare.com
Background The heterogeneity of hepatocellular carcinoma (HCC) poses a challenge for
accurate prognosis prediction. DNA damage repair genes (DDRGs) have an impact on a …

[HTML][HTML] A comprehensive analysis of alterations in DNA damage repair pathways reveals a potential way to enhance the radio-sensitivity of esophageal squamous …

G Wang, S Guo, W Zhang, Z Li, J Xu, D Li… - Frontiers in …, 2020 - frontiersin.org
Esophageal squamous cell cancer (ESCC) is a common malignancy with a poor 5-year
overall survival in China. Altered DNA damage repair (DDR) pathways are associated with a …

[HTML][HTML] Identification of a prognostic signature associated with DNA repair genes in ovarian cancer

H Sun, D Cao, X Ma, J Yang, P Peng, M Yu… - Frontiers in …, 2019 - frontiersin.org
Introduction: Ovarian cancer is a highly malignant cancer with a poor prognosis. At present,
there is no accurate strategy for predicting the prognosis of ovarian cancer. A prognosis …