Tyrosinase ultimately controls the melanogenesis rate of the skin, and tanning and haircare
products generally induce the activation of tyrosinase. Moreover, various enzymes, including …

The objectives of this study were to investigate the melanogenetic potentials of the naturally
occurring 7-hydroxy coumarin derivatives 7-hydroxy 5, 6-dimethoxycoumarin (7H-5, 6DM), 7 …

Background: Melanin in the skin is the defense against the harmful UV radiation, which is
considered as one of the major risk factors for skin cancer. The compound 7, 8 …

We investigated the effects of four coumarin derivatives, namely, 6-methylcoumarin, 7-
methylcoumarin, 4-hydroxy-6-methylcoumarin, and 4-hydroxy-7-methylcoumarin, which …

Psoralen, a major furocoumarin component of the Fructus Psoralen (FP), in combination with
ultraviolet radiation, cures abnormal pigmentation disorder. In a previous study, we …

Background Melanogenesis, or the biosynthesis of melanin, plays a critical role in the
pigmentation of skin, hair, and eyes. Reduced melanogenesis may lead to depigmentation …

Caffeic acid phenethyl ester (1), a natural compound found in various plants and propolis, is
a well-known anti-inflammatory, immunomodulatory, and cytotoxic agent. The present study …

In order to understand the effect of structure–activity relationships on melanogenesis using
B16 melanoma cells, 19 quercetin derivatives were synthesized. Among the synthesized …

Diphlorethohydroxycarmalol (DPHC) is a marine polyphenolic compound derived from
brown alga Ishige okamurae. A previously study has suggested that DPHC possesses …

Protocatechuic aldehyde (PA) is a naturally occurring phenolic compound that is a potent
inhibitor of mushroom tyrosinase. However, the molecular mechanisms of the anti …