Dual stimulation of MyD88-dependent Toll-like receptors induces synergistically enhanced production of inflammatory cytokines in murine bone marrow-derived …
D Mitchell, M Yong, W Schroder, M Black… - The Journal of …, 2010 - academic.oup.com
Abstract Background. Triggering Toll-like receptors (TLRs) on dendritic cells (DCs) induces
inflammatory cytokine production necessary for T helper type 1 immunity. The present study …
inflammatory cytokine production necessary for T helper type 1 immunity. The present study …
Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinases
D Mitchell, C Olive - Molecular immunology, 2010 - Elsevier
Production of chemokines in dendritic cells (DCs) may be crucial in modulating immune
responses generated through Toll-like receptor (TLR)-mediated recognition of microbial …
responses generated through Toll-like receptor (TLR)-mediated recognition of microbial …
Toll-like receptor (TLR) 2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells
F Vanhoutte, C Paget, L Breuilh, J Fontaine… - Immunology letters, 2008 - Elsevier
Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by
dendritic cells (DCs) and in the induction of immune responses. Few studies have been …
dendritic cells (DCs) and in the induction of immune responses. Few studies have been …
Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10
S Thoma-Uszynski, SM Kiertscher… - The Journal of …, 2000 - journals.aai.org
Abstract Mammalian Toll-like receptors (TLRs) are required for cell activation by bacterial
lipoproteins (bLP) and LPS. Stimulation of monocytes with bLP and LPS results in a TLR …
lipoproteins (bLP) and LPS. Stimulation of monocytes with bLP and LPS results in a TLR …
Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells
F Re, JL Strominger - Journal of Biological Chemistry, 2001 - ASBMB
Toll-like receptors (TLRs) mediate cell activation by various microbial products. Here, we
demonstrate that activation of dendritic cells by TLR2 or TLR4 agonists, although it led to …
demonstrate that activation of dendritic cells by TLR2 or TLR4 agonists, although it led to …
Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T …
HR Bohnenkamp, KT Papazisis, JM Burchell… - Cellular …, 2007 - Elsevier
Toll-like receptors (TLRs) recognise specific molecular signatures of pathogens and trigger
antimicrobial defence responses. Thereby, two independent signalling pathways can be …
antimicrobial defence responses. Thereby, two independent signalling pathways can be …
Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
T Warger, P Osterloh, G Rechtsteiner, M Fassbender… - Blood, 2006 - ashpublications.org
Toll-like receptors (TLRs) are able to interact with pathogen-derived products and their
signals induce the coordinated activation of innate and adaptive immune mechanisms …
signals induce the coordinated activation of innate and adaptive immune mechanisms …
Endotoxin can induce MyD88‐deficient dendritic cells to support Th2 cell differentiation
T Kaisho, K Hoshino, T Iwabe, O Takeuchi… - International …, 2002 - academic.oup.com
Toll‐like receptor (TLR) signaling activates dendritic cells (DC) to secrete proinflammatory
cytokines and up‐regulate co‐stimulatory molecule expression, thereby linking innate and …
cytokines and up‐regulate co‐stimulatory molecule expression, thereby linking innate and …
Differential regulation of Toll‐like receptor signalling in spleen and Peyer's patch dendritic cells
Toll‐like receptor (TLR) signalling shapes dendritic cell (DC) responses by inducing co‐
stimulatory molecule up‐regulation and cytokine secretion while TLR regulatory proteins …
stimulatory molecule up‐regulation and cytokine secretion while TLR regulatory proteins …
Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles
Dendritic cells (DCs) discriminate different microbial pathogens and induce T-cell responses
of appropriate effector phenotypes accordingly. Microbial recognition and differentiation are …
of appropriate effector phenotypes accordingly. Microbial recognition and differentiation are …
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