The ability of the fungal pathogen Cryptococcus neoformans to evade the mammalian innate
immune response and cause disease is partially due to its ability to respond to and survive …

Cryptococcus neoformans is a human fungal pathogen that survives exposure to stresses
during growth in the human host, including oxidative and nitrosative stress, high …

The thioredoxin system, consisting of thioredoxin, thioredoxin reductase and NADPH, is
known to protect cells against oxidative stress. This disulphide reducing system is present in …

Cryptococcus neoformans is one of the few environmental fungi that can survive within a
mammalian host and cause disease. Although many of the factors responsible for …

We studied superoxide dismutases (SODs) in the encapsulated yeast Cryptococcus
neoformans (Cn) variety gattii to analyse the role of mitochondrial MnSOD (SOD2) in fungal …

The ability of the opportunistic fungal pathogen Cryptococcus neoformans to resist oxidative
stress is one of its most important virulence related traits. To cope with the deleterious effect …

Cryptococcus neoformans is a fungal pathogen most commonly causing meningitis in
immunocompromised patients. Current therapies are inadequate, and novel antifungal …

The ability to sense and adapt to a hostile host environment is a crucial element for virulence
of pathogenic fungi, including Cryptococcus neoformans. These cellular responses are …

Cryptococcus neoformans is an opportunistic fungal pathogen that at its peak epidemic
levels caused an estimated million cases of cryptococcal meningitis per year worldwide …

Paracoccidioidomycosis (PCM) is an endemic disease in Latin America caused by species
belonging to the genus Paracoccidioides. During infection, immune cells present a variety of …