Low triiodothyronine predicts mortality in critically ill patients

KVSH Kumar, U Kapoor, R Kalia… - Indian journal of …, 2013 - journals.lww.com
Objective: Alteration in thyroid hormones are seen in critically ill patients admitted to
intensive care units. Our objective was to study the thyroid hormone profile, prolactin and …

Non-thyroidal illness in the ICU: a syndrome with different faces

G Van den Berghe - Thyroid, 2014 - liebertpub.com
Background: Critically ill patients typically present with low or low-normal plasma thyroxine,
low plasma triiodothyronine (T3), increased plasma reverse T3 (rT3) concentrations, in the …

[PDF][PDF] The hypothalamus-pituitary-thyroid axis in critical illness

L Mebis, G Van den Berghe - Neth J Med, 2009 - njmonline.nl
333 november 2 0 0 9, vol. 6 7, no 1 0 hormone (TRH) is released which stimulates the
pituitary to secrete thyroid-stimulating hormone (thyrotropin or TSH). TSH in turn drives the …

Changes within the thyroid axis during the course of critical illness

L Mebis, L Langouche, G Berghe - Acute Endocrinology, 2008 - Springer
Thyroid hormones are indispensable for normal growth, development and metabolism of
virtually every cell and organ (1, 2). The secretion of thyroid hormone is regulated by the …

Low triiodothyronine syndrome: a prognostic marker for outcome in sepsis?

S Meyer, P Schuetz, M Wieland, C Nusbaumer… - Endocrine, 2011 - Springer
There is ongoing controversy as to whether hormonal changes of the euthyroid sick
syndrome are predictors of poor outcome in sepsis and critical illness. In this prospective …

Suppression of the thyrotropin response to thyrotropin-releasing hormone and its association with severity of critical illness

S Sumita, Y Ujike, A Namiki, H Watanabe… - Critical care …, 1994 - journals.lww.com
Objective: To study whether the suppression of the thyrotropin (thyroid-stimulating hormone,
TSH) response to thyrotropin-releasing hormone (TRH) correlates with severity of illness …

The identification of thyroid dysfunction in surgical sepsis

SR Todd, V Sim, LJ Moore, KL Turner… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND Studies have documented a correlation between hypothyroxinemia and
mortality in critically ill patients; however, there are limited data in sepsis. The objective of …

Management of hypothyroidism and hyperthyroidism in the intensive care unit

MD Ringel - Critical care clinics, 2001 - Elsevier
Alterations in thyroid function occur commonly in critically ill patients; however, they are
rarely the primary cause of admission to the intensive care unit (ICU). In this article, the …

Association between thyroid function tests at baseline and the outcome of patients with sepsis or septic shock: a systematic review

AG Angelousi, DE Karageorgopoulos… - European journal of …, 2011 - academic.oup.com
Introduction The severity of critical illness is associated with various patterns of thyroid
hormone abnormalities. We sought to evaluate whether the outcome of patients with …

Beyond Low Plasma T3: Local Thyroid Hormone Metabolism during Inflammation and Infection

A Boelen, J Kwakkel, E Fliers - Endocrine reviews, 2011 - academic.oup.com
Decreased serum thyroid hormone concentrations in severely ill patients were first reported
in the 1970s, but the functional meaning of the observed changes in thyroid hormone levels …