Relationship of admission thyroid function tests to outcome in critical illness

DC Ray, GB Drummond, E Wilkinson, GJ Beckett - Anaesthesia, 1995 - Wiley Online Library
One hundred and eighty patients had serum thyrotropin, total triiodothyronine and free
thyroxine concentrations measured within 3h of admission to the Intensive Therapy Unit to …

[HTML][HTML] Effects of thyroid hormone on tissue hypoxia: relevance to sepsis therapy

AI Lourbopoulos, IS Mourouzis, AG Trikas… - Journal of Clinical …, 2021 - mdpi.com
Tissue hypoxia occurs in various conditions such as myocardial or brain ischemia and
infarction, sepsis, and trauma, and induces cellular damage and tissue remodeling with …

Serum 3,3′,5′-Triiodothyronine (rT3) and 3,5,3′-Triiodothyronine/rT3 Are Prognostic Markers in Critically Ill Patients and Are Associated with Postmortem Tissue …

RP Peeters, PJ Wouters, H van Toor… - The Journal of …, 2005 - academic.oup.com
Introduction and Methods: Critical illness is associated with reduced TSH and thyroid
hormone secretion, and with changes in peripheral thyroid hormone metabolism, resulting in …

Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness

Y Debaveye, B Ellger, L Mebis, VM Darras… - Thyroid, 2008 - liebertpub.com
Background: The low plasma triiodothyronine (T3) observed during prolonged critical illness
can be explained in part by suppressed hepatic deiodinase type I (D1) and increased D3 …

Thyroid hormone levels and their relationship to survival in children with bacterial sepsis and septic shock

D Yıldızdaş, N Önenli-Mungan, Η Yapıcıoğlu… - Journal of Pediatric …, 2004 - degruyter.com
Objectives: Reported studies have showed alter-nations of thyroid hormones in critical
illness mostly in adults and some in children. In this study, we aimed to measure thyroid …

Effects of substitution and high-dose thyroid hormone therapy on deiodination, sulfoconjugation, and tissue thyroid hormone levels in prolonged critically ill rabbits

Y Debaveye, B Ellger, L Mebis, TJ Visser… - …, 2008 - academic.oup.com
To delineate the metabolic fate of thyroid hormone in prolonged critically ill rabbits, we
investigated the impact of two dose regimes of thyroid hormone on plasma 3, 3 …

[HTML][HTML] Serum triiodothyronine levels and inflammatory cytokine production capacity

MP Rozing, RGJ Westendorp, AB Maier, CA Wijsman… - Age, 2012 - Springer
Increasing evidence suggests that pro-inflammatory cytokines are at play in lowering
peripheral thyroid hormone levels during critical illness. Conversely, thyroid hormones have …

Serum thyroid hormone profile in critically III children

JC Suvarna, CN Fande - The Indian Journal of Pediatrics, 2009 - Springer
Objective To study thyroid hormone profile in critically ill children and its correlation to
disease severity and clinical outcome. Methods Total serum triiodothyronine (T3), thyroxine …

Thyroid function in critically ill patients

E Fliers, AC Bianco, L Langouche… - The lancet Diabetes & …, 2015 - thelancet.com
Patients in the intensive care unit (ICU) typically present with decreased concentrations of
plasma tri-iodothyronine, low thyroxine, and normal range or slightly decreased …

HYpothyroxinemia in critically iii patients as a predictor of high mortality

MF Slag, JE Morley, MK Elson, TW Crowson, FQ Nuttall… - Jama, 1981 - jamanetwork.com
Thyroid function was measured in 86 patients hospitalized in an intensive care unit. Two
patients were found to have primary hypothyroidism and were excluded from the study …