Hepatitis B virus (HBV) infection is one the leading risk factors for chronic hepatitis, liver
fibrosis, cirrhosis and hepatocellular cancer (HCC), which are a major global health …

Chronic hepatitis B virus (HBV) infection is one of the high-risk factors for human HCC.
Despite the integration of virus DNA and the oncoprotein HBx, chronic necroinflammation …

Hepatitis B virus (HBV) is responsible for approximately 350 million chronic infections
worldwide and is a leading cause of broad-spectrum liver diseases such as hepatitis …

Host immune responses induced by hepatitis B virus (HBV) infection not only substantially
drive disease progression, but also significantly influence efficacy of antiviral treatments in …

More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …

A great effort of research has been devoted in the last few years to developing new anti-HBV
therapies of finite duration that also provide effective sustained control of virus replication …

Hepatitis B virus (HBV) can replicate within hepatocytes without causing direct cell damage.
The host immune response is, therefore, not only essential to control the spread of virus …

Hepatitis B virus (HBV) infection can lead to several severe liver diseases, including
hepatitis, cirrhosis and hepatocellular carcinoma, although the underlying mechanisms …

Background and aims HBV infection represents a major health problem worldwide, but the
immunological mechanisms by which HBV causes chronic persistent infection remain only …

Non-specific immune responses to antigens have been demonstrated as being enhanced
during chronic hepatitis B virus (HBV) infection. Here, we evaluated the role of interleukin-10 …