The risk of colorectal cancer is reduced among users of oral contraceptives or menopausal
hormone therapy, but associations with reproductive characteristics that are markers of a …

Background There are conflicting data regarding the role of sex hormones in colorectal
cancer development. Whereas clinical trials data indicate that hormone therapy use reduces …

We evaluated colorectal cancer risk associated with the duration and recency of specific
menopausal hormone therapy formulations (ie, unopposed estrogen versus estrogen plus …

Observational epidemiologic studies and randomized trials have reported a protective effect
of oral hormonal replacement therapy on risk of colorectal cancer. Only one previous …

Background Hormone-replacement therapy (HRT) is associated with lower colorectal cancer
(CRC) risk among postmenopausal women. However, little is known about the effects of …

Differences in morbidity rates between males and females have been reported for many
cancer sites. Specifically, in the colon, cancers in females are more commonly detected in …

Background: A potential protective role for estrogen in colon carcinogenesis has been
suggested based on exogenous hormone use, but it is unclear from previous studies …

Background: Postmenopausal hormone therapy use has been associated with lower
colorectal cancer risk in observational studies. However, the role of endogenous sex …

Little is known about the effects of various types, modes, and routes of hormone replacement
therapy (HRT) on the risk of colorectal cancer (CRC) among postmenopausal women. We …

Background Postmenopausal hormone therapy (HRT) and oral contraceptive (OC) use have
in several studies been reported to be associated with a decreased colorectal cancer (CRC) …