Background It has been shown by various diagnostic methodologies that angiotensin
receptor blockage reduces left ventricular mass, improves diastolic function and increases …

Diabetes mellitus (DM) is a major risk factor for heart failure, independent of coronary artery
disease or hypertension (HT). Therefore, our study was designed to examine the …

Left ventricular hypertrophy (LVH) is an important characteristic of hypertensive heart
disease. Renin-angiotensin system (RAS) blockers have been shown to be effective drugs …

Purpose Myocardial fibrosis (MF) is an unavoidable complication in patients with
hypertensive heart disease. Valsartan, a widely used antihypertensive drug, was reported to …

Aim To evaluate the antihypertensive efficacy of angiotensin converting enzyme inhibitor
(ACEI) benazepril in combination with AT1 receptor antagonist valsartan and their effect on …

Abstract Enalapril maleate (MK 421), and hydrochlorothiazide were used to evaluate the
control of hypertension and reversal of myocardial hypertrophy in Dahl sensitive (DS) and …

Bradykinin 2 receptor (B2R) deficiency predisposes to cardiac hypertrophy and
hypertension. The pathways mediating these effects are not known. Two-month-old B2R …

OBJECTIVES AND BACKGROUND: Recent evidence has revealed that aldosterone (ALDO)
is produced in the vasculature, and acts directly in the cardiovascular system. This study was …

OBJECTIVE: To evaluate the effect of spironolactone on ventricular stiffness in
spontaneously hypertensive adult rats subjected to high salt intake. INTRODUCTION: High …

Benazepril, an angiotensin-converting enzyme inhibitor, and candesartan, an angiotensin
receptor blocker, are common drugs for treating hypertension. This study aimed to …