A randomized, noninferiority trial comparing ICS+ LABA with ICS+ LABA+ LAMA in asthma-COPD overlap (ACO) treatment: the ACO Treatment with Optimal …

SY Park, S Kim, JH Kim, SH Kim, T Lee… - The Journal of Allergy …, 2021 - Elsevier
Background Current guidelines for the treatment of asthma and chronic obstructive
pulmonary disease overlap (ACO) recommend initial treatment using inhaled corticosteroids …

Management of asthma COPD overlap

DJ Maselli, NA Hanania - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective To review the latest literature on management approaches to patients with asthma
chronic obstructive pulmonary disease (COPD) overlap (ACO). Data Sources Studies and …

[HTML][HTML] Effect of triple therapy in patients with asthma-COPD overlap

Y Ishiura, M Fujimura, N Ohkura, J Hara… - … Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Objective: Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is of
increasing interest because ACO patients have significantly worse outcomes, leading to …

Comparative safety and effectiveness of inhaled bronchodilators and corticosteroids for treating asthma–COPD overlap: a systematic review and meta-analysis

JE Amegadzie, J Gorgui, L Acheampong… - Journal of …, 2021 - Taylor & Francis
Objective To determine the safety and effectiveness of current pharmacotherapies consisting
of long-acting beta2-agonist (LABA) and/or inhaled corticosteroids (ICS) in patients with …

Therapeutic approaches of asthma and COPD overlap

M Kondo, J Tamaoki - Allergology International, 2018 - jstage.jst.go.jp
abstract Asthma and COPD overlap (ACO) is an important clinical phenotype, due to the low-
health-related quality of life (QOL), rapid decline in lung function, frequent exacerbation, and …

A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease

A D'Urzo, JF Donohue, P Kardos… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Inhaled corticosteroids (ICS)(in fixed combinations with long-acting β2-agonists
[LABAs]) are frequently prescribed for patients with chronic obstructive pulmonary disease …

Benefits of LAMA in patients with asthma-COPD overlap: a systematic review and meta-analysis

J Qin, G Wang, D Han - Clinical Immunology, 2022 - Elsevier
Purpose A systematic review and meta-analysis to determine the efficacy of long-acting
muscarinic antagonist (LAMA) in patients with asthma-COPD overlap (ACO) was conducted …

Use of ICS/LABA combinations or LAMA is associated with a lower risk of acute exacerbation in patients with coexistent COPD and asthma

VYF Su, KY Yang, YH Yang, YH Tsai, DW Perng… - The Journal of Allergy …, 2018 - Elsevier
Background Based on current guidelines, more research is urgently needed to guide
appropriate treatment for patients with asthma-chronic obstructive pulmonary disease …

Pharmacologic management strategies of asthma-chronic obstructive pulmonary disease overlap

NA Hanania, M Miravitlles - Immunology and Allergy …, 2022 - immunology.theclinics.com
Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is a term applied to
patients with clinical features of both asthma and COPD. ACO has been associated with …

Treatment trends in patients with asthma–COPD overlap syndrome in a COPD cohort: findings from a real-world survey

B Ding, M Small - … journal of chronic obstructive pulmonary disease, 2017 - Taylor & Francis
Background Asthma and chronic obstructive pulmonary disease (COPD) overlap syndrome
(ACOS) is an increasingly recognized phenotype. Few randomized clinical trials have been …