Epidemiological and experimental data strongly suggest that type 1 diabetes occurs as a
detrimental combination of genetic predisposition and environmental triggering factors …

Virus infections have been linked to the induction of autoimmunity and disease development
in human type 1 diabetes. Experimental models have been instrumental in deciphering …

The role of viral infection in the pathogenesis of type 1 diabetes in humans remains an open
question. Viruses are variously thought to be causative, preventive, or irrelevant. The rat …

Studies performed in humans and animal models have implicated the environment in the
etiology of type 1 diabetes (T1D), but the nature and timing of the interactions triggering β …

We investigated the potential association between viruses and insulin-dependent(type 1)
diabetes (IDDM) by developing a transgenic mouse model. By inserting into these mice a …

During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly,
reaching percentages of 3% annually worldwide. This increase suggests that besides …

Type 1 diabetes mellitus (T1DM) is a multi-factorial autoimmune disease determined by the
interaction of genetic, environmental and immunologic factors. One of the environmental risk …

Type 1 diabetes is an autoimmune disease characterized by the destruction of insulin-
producing pancreatic β-cells. Even though extensive scientific research has yielded …

Type 1 diabetes mellitus (T1D) is a multi-factorial autoimmune disease determined by the
interaction of genetic, environmental and immunologic factors. Data from experimental …

Virus infections have been implicated in both initiation of and protection from autoimmune
diseases, such as type 1 diabetes (T1D). In this review we intend to reflect on recent …