Viral infections and autoimmune diabetes
A Alba, R Planas, J Verdaguer… - Inmunología (1987 …, 2005 - pesquisa.bvsalud.org
RESUMEN La diabetes tipo 1 (DT1) es una enfermedad autoinmunitaria causada por la
destrucción de las células beta pancreáticas productoras de insulina. La patogénesis de …
destrucción de las células beta pancreáticas productoras de insulina. La patogénesis de …
The contribution of viruses and innate immune system in the pathogenesis of type 1 diabetes
Type 1 diabetes (T1D) is a chronic autoimmune disease, characterized by the selective
dysfunction and destruction of pancreatic β-cells, resulting in insulin deficiency (1). While the …
dysfunction and destruction of pancreatic β-cells, resulting in insulin deficiency (1). While the …
Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens
VA Thomas, BA Woda, ES Handler, DL Greiner… - Diabetes, 1991 - Am Diabetes Assoc
Autoimmune diabetes mellitus affects> 50% of diabetes-prone BB (DP BB) rats but< 1% of
diabetes-resistant BB (DR BB) rats. We report an outbreak of spontaneous diabetes among …
diabetes-resistant BB (DR BB) rats. We report an outbreak of spontaneous diabetes among …
Role of viruses and other microbes in the pathogenesis of type 1 diabetes
A Kondrashova, H Hyoety - International reviews of immunology, 2014 - Taylor & Francis
Type 1 diabetes is caused by an immune-mediated destruction of insulin producing beta-
cells in the pancreas. The risk of the disease is determined by interactions between more …
cells in the pancreas. The risk of the disease is determined by interactions between more …
Animal models of human type 1 diabetes
M Von Herrath, GT Nepom - Nature immunology, 2009 - nature.com
Type 1 diabetes is an immune-mediated disease in which pancreatic insulin-producing beta
cells are damaged and destroyed. Animal models have served a prominent function in the …
cells are damaged and destroyed. Animal models have served a prominent function in the …
Role of viruses in type I diabetes
MG von Herrath, A Holz, D Homann… - Seminars in immunology, 1998 - Elsevier
Viral infections frequently elicit strong cellular and humoral immune responses. This bears
the inherent danger of co-activating autoreactive lymphocytes, either through bystander …
the inherent danger of co-activating autoreactive lymphocytes, either through bystander …
Closing the Circle between the Bedside and the Bench: Toll‐Like Receptors in Models of Virally Induced Diabetes
R Bortell, SC Pino, DL Greiner, D Zipris… - Annals of the New …, 2008 - Wiley Online Library
Animal models provide many strategies to unravel the complex interplay of genetic,
immunologic, and environmental factors involved in the pathogenesis of type 1A …
immunologic, and environmental factors involved in the pathogenesis of type 1A …
Environmental causes: viral causes
H Hyöty - Endocrinology and Metabolism Clinics, 2004 - endo.theclinics.com
Viruses are among the most studied potential environmental triggers of type 1 diabetes
mellitus (T1D). Viruses can cause b-cell damage and diabetes in many mammals [1, 2], and …
mellitus (T1D). Viruses can cause b-cell damage and diabetes in many mammals [1, 2], and …
Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma
KT Coppieters, A Wiberg, SM Tracy… - Clinical & …, 2012 - academic.oup.com
Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW
SERIES Metabolic diseases, host responses, cancer, autoinflammatory diseases, allergy …
SERIES Metabolic diseases, host responses, cancer, autoinflammatory diseases, allergy …