[HTML][HTML] Lipidomes in health and disease: Analytical strategies and considerations

F Wei, S Lamichhane, M Orešič… - TrAC Trends in Analytical …, 2019 - Elsevier
Lipidomics is a rapidly-growing field which focuses on global characterization of lipids at
molecular and systems levels. As small changes in the concentrations of lipids may have …

Contemporary lipidomic analytics: opportunities and pitfalls

C Giles, R Takechi, V Lam, SS Dhaliwal… - Progress in Lipid …, 2018 - Elsevier
Recent advances in analytical techniques have greatly enhanced the depth of coverage,
however lipidomic studies are still restricted to analysing only a subset of known lipids …

Lipidomics in biomedical research-practical considerations

T Hyötyläinen, L Ahonen, P Pöhö, M Orešič - Biochimica et Biophysica Acta …, 2017 - Elsevier
Lipids have many central physiological roles including as structural components of cell
membranes, energy storage sources and intermediates in signaling pathways. Lipid-related …

Informatics and computational strategies for the study of lipids

M Orešič - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2011 - Elsevier
The ability to translate vast amounts of information, as obtained from lipidomic analysis, into
the knowledge and understanding of biological phenomena is an important challenge faced …

[PDF][PDF] Lipidomics in health and diseases-beyond the analysis of lipids

M Li, P Fan, Y Wang - Journal of Glycomics & Lipidomics, 2014 - hub.hku.hk
The role of lipids in human health and disease is taking the center stage. In the last decades,
there has been an intense effort to develop suitable methodologies to discover, identify, and …

Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

NR Zhang, NG Hatcher, K Ekroos, K Kedia… - Journal of Lipid …, 2022 - ASBMB
A major challenge of lipidomics is to determine and quantify the precise content of complex
lipidomes to the exact lipid molecular species. Often, multiple methods are needed to …

Liquid chromatography techniques in lipidomics research

M Lange, Z Ni, A Criscuolo, M Fedorova - Chromatographia, 2019 - Springer
Lipids represent a very diverse group of compounds with a high variety of physicochemical
properties determining their functional activities. For omics-wide identification of lipid …

Extraction, chromatographic and mass spectrometric methods for lipid analysis

S Pati, B Nie, RD Arnold… - Biomedical …, 2016 - Wiley Online Library
Lipids make up a diverse subset of biomolecules that are responsible for mediating a variety
of structural and functional properties as well as modulating cellular functions such as …

Mouse lipidomics reveals inherent flexibility of a mammalian lipidome

MA Surma, MJ Gerl, R Herzog, J Helppi, K Simons… - Scientific reports, 2021 - nature.com
Lipidomics has become an indispensable method for the quantitative assessment of lipid
metabolism in basic, clinical, and pharmaceutical research. It allows for the generation of …

Lipidomics: techniques, applications, and outcomes related to biomedical sciences

K Yang, X Han - Trends in biochemical sciences, 2016 - cell.com
Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …